RB-120
RB-120 (benzyl (2S)-2-{[(2S)-2-({[(2S)-2-amino-4-methylsulfanylbutyl]disulfanyl}methyl)-3-phenylpropanoyl]amino}propanoate) is an orally active analog of the drug RB-101. It acts as an enkephalinase inhibitor, which is used in scientific research. Via intravenous administration, it is approximately three times as potent as RB-101 or twice as potent as the isolated (S,S) isomer of RB101. However, via i.p. administration it is approximately twice as potent as racemic RB-101 and about as potent as the isolated (S,S) isomer of RB101. During i.v. administration RB120 is approximately twice as weak as morphine in terms of analgesia, however it is 16x weaker during i.p. and p.o. administration.
RB-120
RB-120 (benzyl (2S)-2-{[(2S)-2-({[(2S)-2-amino-4-methylsulfanylbutyl]disulfanyl}methyl)-3-phenylpropanoyl]amino}propanoate) is an orally active analog of the drug RB-101. It acts as an enkephalinase inhibitor, which is used in scientific research. Via intravenous administration, it is approximately three times as potent as RB-101 or twice as potent as the isolated (S,S) isomer of RB101. However, via i.p. administration it is approximately twice as potent as racemic RB-101 and about as potent as the isolated (S,S) isomer of RB101. During i.v. administration RB120 is approximately twice as weak as morphine in terms of analgesia, however it is 16x weaker during i.p. and p.o. administration.
has abstract
RB-120 (benzyl (2S)-2-{[(2S)-2 ...... i.p. and p.o. administration.
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PubChem
Wikipage page ID
57,042,375
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1,011,378,023
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IUPAC name
N-{-2-benzyl-3[-butyldithio]-1-oxopropyl}-l-alanine benzyl ester
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PubChem
54,470,354
SMILES
C[C@@H]NC[C@H]CSSC[C@H]N
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StdInChIKey
XHWYFTNNIZGHRW-PMOQBDJRSA-N
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subject
comment
RB-120 (benzyl (2S)-2-{[(2S)-2 ...... i.p. and p.o. administration.
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label
RB-120
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