Trioxsalen
Trioxsalen (trimethylpsoralen (TMP), trioxysalen (INN) or Trisoralen) is a furanocoumarin and a psoralen derivative. It is obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms. In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage. The compound is also being explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutan
primaryTopic
Trioxsalen
Trioxsalen (trimethylpsoralen (TMP), trioxysalen (INN) or Trisoralen) is a furanocoumarin and a psoralen derivative. It is obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms. In research it can be conjugated to dyes for confocal microscopy and used to visualize sites of DNA damage. The compound is also being explored for development of antisense oligonucleotides that can be cross-linked specifically to a mutan
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Il trimetilpsoralene, o trioxs ...... piante, principalmente dalla .
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Trioxsalen (trimethylpsoralen ...... ersions can also be obtained..
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Trioxsalen ist eine chemische ...... cumarine und Psoralenderivate.
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Trioxsaleno é um fármaco que a ...... lar para formação de melanina.
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يُعد تري أوكسالين Trioxsalen ( ...... folia. و هو من مضادات الصدفية.
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IUPAC name
2,5,9-Trimethyl-7H-furo[3,2-g][1]benzopyran-7-one
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13,270,017
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1,020,076,318
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Il trimetilpsoralene, o trioxs ...... piante, principalmente dalla .
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Trioxsalen (trimethylpsoralen ...... linked specifically to a mutan
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Trioxsalen ist eine chemische ...... cumarine und Psoralenderivate.
@de
Trioxsaleno é um fármaco que a ...... lar para formação de melanina.
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يُعد تري أوكسالين Trioxsalen ( ...... folia. و هو من مضادات الصدفية.
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label
Trimetilpsoralene
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Trioxsalen
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Trioxsalen
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Trioxsaleno
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تري أوكسالين
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