Sequence requirements for viral RNA replication and VPg uridylylation directed by the internal cis-acting replication element (cre) of human rhinovirus type 14.Complexes of poliovirus serotypes with their common cellular receptor, CD155cis-acting RNA signals in the NS5B C-terminal coding sequence of the hepatitis C virus genomeProfile of Eckard Wimmer. Interview by Sujata GuptaVirus attenuation by genome-scale changes in codon pair biasCis-acting RNA elements in human and animal plus-strand RNA virusesPutting synthesis into biology: a viral view of genetic engineering through de novo gene and genome synthesisSynthetic viruses: a new opportunity to understand and prevent viral diseaseCrystal structure of CD155 and electron microscopic studies of its complexes with poliovirusesEvidence for emergence of diverse polioviruses from C-cluster coxsackie A viruses and implications for global poliovirus eradicationStimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproThe C-Terminal Hydrophobic Domain of Hepatitis C Virus RNA Polymerase NS5B Can Be Replaced with a Heterologous Domain of Poliovirus Protein 3ARecruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155, a vitronectin and poliovirus receptor that localizes to alpha(v)beta3 integrin-containing membrane microdomainsInteraction of the poliovirus receptor CD155 with the dynein light chain Tctex-1 and its implication for poliovirus pathogenesisPyrite-induced hydroxyl radical formation and its effect on nucleic acidsDirect interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesisBinding of glutathione to enterovirus capsids is essential for virion morphogenesisAn interaction between glutathione and the capsid is required for the morphogenesis of C-cluster enterovirusesThe test-tube synthesis of a chemical called poliovirus. The simple synthesis of a virus has far-reaching societal implicationsEvaluation of the attenuation, immunogenicity, and efficacy of a live virus vaccine generated by codon-pair bias de-optimization of the 2009 pandemic H1N1 influenza virus, in ferrets.Live attenuated influenza virus vaccines by computer-aided rational design.HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage.Identification of cellular proteins enhancing activities of internal ribosomal entry sites by competition with oligodeoxynucleotidesA C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesisStimulation of poliovirus synthesis in a HeLa cell-free in vitro translation-RNA replication system by viral protein 3CDproPoliomyelitis in transgenic mice expressing CD155 under the control of the Tage4 promoter after oral and parenteral poliovirus inoculationChemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template.Poliovirus and poliomyelitis: a tale of guts, brains, and an accidental event.Mutation of a single conserved nucleotide between the cloverleaf and internal ribosome entry site attenuates poliovirus neurovirulenceExpression of the human poliovirus receptor/CD155 gene is activated by sonic hedgehog.Identification of two functionally redundant RNA elements in the coding sequence of poliovirus using computer-generated designPicornavirus morphogenesis.Reduction of the rate of poliovirus protein synthesis through large-scale codon deoptimization causes attenuation of viral virulence by lowering specific infectivityAttenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization.Polypyrimidine tract binding protein-1 (PTB1) is a determinant of the tissue and host tropism of a human rhinovirus/poliovirus chimera PV1(RIPO).Vaccination against polio should not be stopped.Functional dissection of a poliovirus cis-acting replication element [PV-cre(2C)]: analysis of single- and dual-cre viral genomes and proteins that bind specifically to PV-cre RNAA host-specific, temperature-sensitive translation defect determines the attenuation phenotype of a human rhinovirus/poliovirus chimera, PV1(RIPO).Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector.Large-scale recoding of an arbovirus genome to rebalance its insect versus mammalian preference.
P50
Q24537790-613F40CE-FB19-49AD-8714-631D7900B40AQ24554469-2BDB6F91-998D-408C-979E-518FB2D8085CQ24563876-DF63FE34-EB47-4663-998E-17CB52FE165DQ24624402-F2788E4C-33CA-4104-BA4A-FE09B3365ABFQ24644457-666A91D7-6D49-4D7C-9399-B880C093E73CQ24649975-C728DE10-EA53-4034-AB58-3C53B1A654FFQ24650468-95C9FB27-B10A-4FE9-BFA3-849AA3866409Q24650817-94664B98-D03C-4C13-B817-7369E965F13BQ24653737-9A6B8F9C-41B2-4700-8FD6-28960B864C0BQ24683132-7C36BB52-3697-4744-9552-56B59AC0E53BQ24812615-104EE6F2-535A-4A88-B29C-BE7F44FB9F87Q27477611-0DE7EA48-55EC-41EF-A7F9-FE1425B63250Q28205394-1D402935-A8F5-45C0-BADF-1150D93743F4Q28212851-E442BD0C-DCCD-43FD-9EE5-A7B0BF097CE4Q28389944-A73069A3-2CBB-44A5-95FE-ACE98661942CQ28475329-CA9E8BA7-C5C5-4461-A58E-229AF1C06600Q28537703-9B711342-642B-4ADD-ADFE-502B21203113Q28537710-5C9C416E-CE1F-4913-A488-E211CEC2EC56Q28768487-1E670D18-062B-440C-9215-902AF08851C3Q30382343-97BE1F73-E619-4E38-9611-CDF1673B8B31Q30390286-67C9FA03-DB67-4F4F-B45D-5CE178263500Q30945296-4DD9F187-50F2-4034-B89D-70CA209E60E0Q31049788-687032B6-669C-4C1E-B02B-A75D03DE1719Q33635090-3E02B3E7-5D13-4065-B6C5-63DC08EE49C2Q33780515-FA364DA5-7A7F-4B8A-88D8-85D5FCBDC989Q33918627-C3638F09-E90C-47C9-9673-20710D30B171Q33960127-A17FFAA2-B298-4C34-84D2-6B0771B450E1Q33987017-BB8CB287-CC0C-49AE-9FA5-7460B77538C9Q34124035-54E9F4A8-7600-4B4C-BD9D-C82940430AA5Q34126107-FB80978A-E1CC-4EFC-872C-FC39046B8E2FQ34293577-7DB82940-36EA-4290-BD72-DC4C21DC264FQ34297832-3CEED7DA-D1D5-405A-A044-644C0797CBFFQ34566179-4E087982-D9E6-47EC-BC2C-CFE6586A2147Q34583420-27D54EB4-3DDA-48B1-8519-BEA2C8CAECB3Q34674160-C964A315-7D6B-4499-B6BE-EE7F20CA3EAEQ34707400-46BEF212-A992-44BC-BDCE-24006F0615B5Q34975487-C309C3CA-0663-47D1-9415-A58E10E1EE5FQ35077681-9910C525-4CB8-4AC2-A3C5-8390500A00F8Q35180550-ADDBB3DB-43B2-4ADC-A38F-E71B95B3A7D8Q35484845-744B025B-60A3-40DC-92D6-BCF9AC69530F
P50
description
American virologist
@en
Amerikaans bioloog
@nl
US-amerikanischer Virologe
@de
ahli biologi asal Jerman
@id
professor académico alemão
@pt
tysk professor
@da
tysk professor
@sv
usona virusologo
@eo
virolojiste american
@lfn
virólogo estadounidense
@es
name
Eckard Wimmer
@ace
Eckard Wimmer
@ast
Eckard Wimmer
@ca
Eckard Wimmer
@cy
Eckard Wimmer
@da
Eckard Wimmer
@de
Eckard Wimmer
@en
Eckard Wimmer
@es
Eckard Wimmer
@fr
Eckard Wimmer
@hu
type
label
Eckard Wimmer
@ace
Eckard Wimmer
@ast
Eckard Wimmer
@ca
Eckard Wimmer
@cy
Eckard Wimmer
@da
Eckard Wimmer
@de
Eckard Wimmer
@en
Eckard Wimmer
@es
Eckard Wimmer
@fr
Eckard Wimmer
@hu
prefLabel
Eckard Wimmer
@ace
Eckard Wimmer
@ast
Eckard Wimmer
@ca
Eckard Wimmer
@cy
Eckard Wimmer
@da
Eckard Wimmer
@de
Eckard Wimmer
@en
Eckard Wimmer
@es
Eckard Wimmer
@fr
Eckard Wimmer
@hu