p-2S-SMAD2/3:SMAD4:MEN1FAM20C substratesFAM20C productsTCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complexCDH1 dimer:CTTNB1:CTTNA1:IQGAP1:MEN1MEN1 binds SMAD2/3:SMAD4 heterotrimerRecruitment of SET1 methyltransferase complexAPC promotes disassembly of beta-catenin transactivation complexIQGAP1 binds CDH1:CTTNB1:CTTNA1 and MEN1
P527
P688
Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcriptionInactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signalingMenin interacts directly with the homeobox-containing protein PemThe tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivationMenin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chainLeukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expressionDirect binding of DNA by tumor suppressor meninMultiple tumor suppressor pathways negatively regulate telomeraseMenin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activationMenin, the product of the MEN1 gene, is a nuclear proteinMenin associates with FANCD2, a protein involved in repair of DNA damageMenin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locusc-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell developmentMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDMenin localizes to chromatin through an ATR-CHK1 mediated pathway after UV-induced DNA damageMenin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitorsHTLV-1 bZIP factor impedes the menin tumor suppressor and upregulates JunD-mediated transcription of the hTERT gene
P921
Q50257938-F0B7EBE0-B0CA-44B0-BD98-898BABA89A2BQ50269397-F3BC484C-CE8E-4708-8659-0AD18D6B04EDQ50269401-AB6CF2F9-0212-49D0-B7EB-EBE1FBB71A29Q50273514-5651A94B-C0F2-4820-B51F-C632D08B26ABQ50274215-A57A2005-C937-4970-BD6E-9F699A221DF9Q50290116-F7E1810E-4559-4D12-909B-A7F37E1EF10CQ50298754-FDACB2EB-8E85-4AF2-BF76-A03428947A5CQ50298764-B04706B1-BDA5-4133-B795-CB7AA66E2411Q50299201-D4E5003D-1A39-4B8C-8425-09BE61460C98
P527
Q22001458-860205AD-3B53-4DF1-94C3-3A4869E0903DQ24290996-CE91582B-1355-4F20-B1CB-EBF830D42E26Q24291549-2D158B88-DE32-4B4A-9244-8B5E72905332Q24291618-2C804966-110A-4B07-863F-E7EA8655A90FQ24295255-10E959CB-B655-4102-B214-611D031486CBQ24297027-91D12133-157C-42AB-B490-77BBA047D5A3Q24301985-AD2F8DE0-6F75-4BA5-BDE7-FDD75FDAF2EDQ24306608-54CCE237-3AA6-4C05-9833-C719EF5DC5FFQ24306677-8F4FF967-3DD7-4D6C-84FE-6D399054BD1CQ24310070-F70857D2-8999-4A2A-B2E5-964DCA18AB19Q24310300-EB9EEEC9-D716-442C-BB36-EEB30D662A30Q24313196-F610B41B-685B-4C1F-9A01-A1783A7B7145Q24313643-1ED60042-0B6B-4D17-A9D1-CB059A5D06C5Q24316533-57D9B7D2-9E5C-456D-9F27-7321A93EEB0EQ24337033-3AF54932-F0CD-4DF4-9302-D82305EE8103Q24337658-309BD3F4-1426-46F9-82B3-B95B2F8A85EEQ28115378-E7414A27-8F5A-4B8E-BFE3-95107A310A58
P921
description
Protein
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Menin 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
MEN1
@cy
Menin 1
@en
Menin 1
@nl
Menin
@de
Менін
@uk
type
label
MEN1
@cy
Menin 1
@en
Menin 1
@nl
Menin
@de
Менін
@uk
altLabel
MEN1
@en
menin
@en
uniprot:O00255
@en
prefLabel
MEN1
@cy
Menin 1
@en
Menin 1
@nl
Menin
@de
Менін
@uk
P637
P638
P680
P681
P682
P705
P352
P6366
P637
P646
P31
P352
P361
P6366
2779469564
P637
NP_001357180
NP_001357188
NP_001357189
NP_001357190
NP_001357191
NP_001357192
P638
P646
/m/03bxxn0
P680
P681
P682
P702
P703
P705
ENSP00000308975
ENSP00000323747
ENSP00000337088
ENSP00000366530
ENSP00000366533
ENSP00000366538
ENSP00000366543
ENSP00000377899
ENSP00000377901
ENSP00000388016