The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation
about
Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chainDirect binding of DNA by tumor suppressor meninMenin stimulates homology-directed DNA repairMenin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activationTumor necrosis factor-alpha-induced IKK phosphorylation of NF-kappaB p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathwayThe 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor geneThe tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.Global gene expression in neuroendocrine tumors from patients with the MEN1 syndromeCrystal structure of menin reveals binding site for mixed lineage leukemia (MLL) proteinMEN1, MEN4, and Carney Complex: Pathology and Molecular GeneticsMenin, the multiple endocrine neoplasia type 1 gene product, exhibits GTP-hydrolyzing activity in the presence of the tumor metastasis suppressor nm23Growth hormone-secreting tumors: genetic aspects and data from animal modelsMultiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4)Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2Reduction of menin expression enhances cell proliferation and is tumorigenic in intestinal epithelial cellsMenin induces apoptosis in murine embryonic fibroblastsConditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissuesmiR-24 regulates menin in the endocrine pancreasA reproducible approach to high-throughput biological data acquisition and integrationIdentification of somatic mutations in parathyroid tumors using whole-exome sequencingMenin links the stress response to genome stability in Drosophila melanogasterMultiple endocrine neoplasia type 1 associated with breast cancer: A case report and review of the literatureRegulation of cyclin B2 expression and cell cycle G2/m transition by meninMenin is a regulator of the stress response in Drosophila melanogasterMenin immunoreactivity in secretory granules of human pancreatic islet cellsThe tumor suppressor protein menin inhibits AKT activation by regulating its cellular localization.Parathyroid tumor development involves deregulation of homeobox genesChallenges and opportunities in targeting the menin-MLL interaction.NF-κB and cancer: a paradigm of Yin-Yang.Menin represses tumorigenesis via repressing cell proliferation.Update on genetic and clinical aspects of primary hyperparathyroidism.Of mice and MEN1: Insulinomas in a conditional mouse knockout.Menin missense mutants associated with multiple endocrine neoplasia type 1 are rapidly degraded via the ubiquitin-proteasome pathway.Insulin regulates menin expression, cytoplasmic localization, and interaction with FOXO1.Impaired transforming growth factor-β (TGF-β) transcriptional activity and cell proliferation control of a menin in-frame deletion mutant associated with multiple endocrine neoplasia type 1 (MEN1).Variable clinical expression in patients with a germline MEN1 disease gene mutation: clues to a genotype-phenotype correlation.Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions.Isolated familial somatotropinomas: clinical and genetic considerationsShort interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.
P2860
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P248
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P2860
The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
The tumor suppressor protein m ...... appaB-mediated transactivation
@ast
The tumor suppressor protein m ...... appaB-mediated transactivation
@en
The tumor suppressor protein m ...... appaB-mediated transactivation
@en-gb
The tumor suppressor protein m ...... appaB-mediated transactivation
@nl
type
label
The tumor suppressor protein m ...... appaB-mediated transactivation
@ast
The tumor suppressor protein m ...... appaB-mediated transactivation
@en
The tumor suppressor protein m ...... appaB-mediated transactivation
@en-gb
The tumor suppressor protein m ...... appaB-mediated transactivation
@nl
prefLabel
The tumor suppressor protein m ...... appaB-mediated transactivation
@ast
The tumor suppressor protein m ...... appaB-mediated transactivation
@en
The tumor suppressor protein m ...... appaB-mediated transactivation
@en-gb
The tumor suppressor protein m ...... appaB-mediated transactivation
@nl
P2093
P2860
P356
P1433
P1476
The tumor suppressor protein m ...... appaB-mediated transactivation
@en
P2093
A M Spiegel
K Y Bilimoria
L J Whitty
S C Chandrasekharappa
S K Agarwal
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204529
P407
P577
2001-08-16T00:00:00Z
P5875
P6179
1047494570