about
P688
Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemiaExpression, purification, and functional analysis of the human serine protease HtrA2Characterization of human HtrA2, a novel serine protease involved in the mammalian cellular stress responseTissue-specific splicing of Omi stress-regulated endoprotease leads to an inactive protease with a modified PDZ motifA serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell deathThe serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motifHtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteinsProteome-wide Identification of HtrA2/Omi SubstratesGRIM-19 associates with the serine protease HtrA2 for promoting cell deathPARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neuronsThe mitochondrial serine protease HtrA2/Omi cleaves RIP1 during apoptosis of Ba/F3 cells induced by growth factor withdrawalBiochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell deathOxidative stress-induced signaling pathways implicated in the pathogenesis of Parkinson's diseaseStructural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/OmiInactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagyThe protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway
P921
Q22011147-264A4ED6-BD42-4896-9A7C-F2BB2A09413AQ22254360-C75901D6-6F36-4B41-97C0-2A5BBDAC428BQ24290181-EBF8EA26-A511-4141-8D19-3A0C8DB827B6Q24290279-E6BB98F1-6E7B-499E-AD07-7235D0148D0AQ24291746-DD2C11D0-BDB0-43E8-A97D-CF18684B4070Q24291797-EC143188-666D-4526-8A91-E62685AD7552Q24291802-E09C3920-38E4-48B6-B391-1E9BF658A1E1Q24294947-B708F6C3-F501-4665-89AD-F44BAA43D308Q24297053-E9C23D23-28F8-4789-9CC2-594C01215A3EQ24297072-8C252831-A8E5-4F6B-8781-AA5297AAD18BQ24298215-5424D599-1B8F-4EE8-BF49-BAFAD0F11C05Q24307730-03A8513E-06B7-4765-AC57-34EE74CDFB84Q24320297-E257AF91-E9CE-47BA-ADC5-15372B6C3BCAQ24337079-0169DDEA-79BE-4C32-9FB2-8B04361DC210Q27638886-E6351CB1-660F-4303-81EC-15E883E1D137Q28116294-B754BE2A-D236-4641-B363-33DFBCCBB353Q28117215-2528ED0D-9A4C-404B-A9A6-A2B9BC724581
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteinë
@sq
proteïne in HtrA serine peptidase 2
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
HtrA serine peptidase 2
@en
type
label
HtrA serine peptidase 2
@en
altLabel
HTRA2
@en
HtrA-like serine protease
@en
Omi stress-regulated endoprotease
@en
epididymis secretory sperm binding protein
@en
high temperature requirement protein A2
@en
protease, serine, 25
@en
serine protease 25
@en
serine protease HTRA2, mitochondrial
@en
serine proteinase OMI
@en
prefLabel
HtrA serine peptidase 2
@en
P361
P637
P680
P681
P682
P705
P352
P31
P352
P527
P637
NP_001308656
NP_001308657
P680
P681
P682
P702
P703
P705
ENSP00000258080
ENSP00000312893
ENSP00000399166