about
P129
P688
MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activationPhosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST)The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylationMammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPARγThe Hippo pathway regulates Wnt/beta-catenin signalingNewly identified stress-responsive protein kinases, Krs-1 and Krs-2MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferationThe Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domainPhosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1The tumor suppressor Mst1 promotes changes in the cellular redox state by phosphorylation and inactivation of peroxiredoxin-1 proteinMammalian NDR/LATS protein kinases in hippo tumor suppressor signalingCloning and characterization of a member of the MST subfamily of Ste20-like kinasesMST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylationRole of the tumor suppressor RASSF2 in regulation of MST1 kinase activityCloning and characterization of a human protein kinase with homology to Ste20Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by RasRASSF2 associates with and stabilizes the proapoptotic kinase MST2A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life spanCaspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1
P921
description
humanes Protein
@de
mammalian protein found in Homo sapiens
@en
menselijk eiwit
@nl
protein
@id
protein
@sv
proteinë
@sq
protèin
@ace
protéine humaine
@fr
بروتين بشري
@ar
name
Serine/threonine kinase 4
@en
Serine/threonine kinase 4
@nl
type
label
Serine/threonine kinase 4
@en
Serine/threonine kinase 4
@nl
altLabel
MST-1
@en
STE20-like kinase MST1
@en
STK4
@en
kinase responsive to stress 2
@en
mammalian STE20-like protein kinase 1
@en
mammalian sterile 20-like 1
@en
serine/threonine-protein kinase 4
@en
serine/threonine-protein kinase Krs-2
@en
prefLabel
Serine/threonine kinase 4
@en
Serine/threonine kinase 4
@nl
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P638
P680
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P705
P352
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P129
P31
P352
P637
NP_001339314
XP_005260587
XP_005260588
XP_005260589
XP_011527320
XP_011527322
XP_016883518
XP_016883519
XP_016883520
P638
P680
P682
P702
P703
P705
ENSP00000361887
ENSP00000361892
ENSP00000443514
ENSP00000479564
ENSP00000482076