The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1
about
Mst1-FoxO signaling protects Naïve T lymphocytes from cellular oxidative stress in miceMST1 is a multifunctional caspase-independent inhibitor of androgenic signaling.Regulation of proapoptotic mammalian ste20-like kinase MST2 by the IGF1-Akt pathwayPhosphoinositide 3-kinase/Akt inhibits MST1-mediated pro-apoptotic signaling through phosphorylation of threonine 120The hippo signaling pathway in development and cancerThe MST/Hippo Pathway and Cell Death: A Non-Canonical AffairYAP-Mediated Mechanotransduction in Skeletal MuscleStructural Comparison of Human Mammalian Ste20-Like KinasesCrucial role for Mst1 and Mst2 kinases in early embryonic development of the mouseCancer biomarker discovery: the entropic hallmark.MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo.Cross-regulation between oncogenic BRAF(V600E) kinase and the MST1 pathway in papillary thyroid carcinomaMST1/MST2 Protein Kinases: Regulation and Physiologic Roles.Mammalian Ste20-like kinase (Mst2) indirectly supports Raf-1/ERK pathway activity via maintenance of protein phosphatase-2A catalytic subunit levels and consequent suppression of inhibitory Raf-1 phosphorylationOverexpression of MYC and EZH2 cooperates to epigenetically silence MST1 expression.PP1A-mediated dephosphorylation positively regulates YAP2 activityAn absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation.Genetic variants in the Hippo pathway predict biochemical recurrence after radical prostatectomy for localized prostate cancer.Competing to coordinate cell fate decisions: the MST2-Raf-1 signaling deviceAberrant large tumor suppressor 2 (LATS2) gene expression correlates with EGFR mutation and survival in lung adenocarcinomas.The phenotype of human STK4 deficiency.Multiple-Localization and Hub Proteins.STK4 regulates TLR pathways and protects against chronic inflammation-related hepatocellular carcinoma.Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease.Protein kinases of the Hippo pathway: regulation and substrates.The Hippo signal transduction network for exercise physiologistsMolecular chaperone Hsp27 regulates the Hippo tumor suppressor pathway in cancer.Caspases and kinases in a death grip.Dendritic cell MST1 inhibits Th17 differentiation.YAP1 and AR interactions contribute to the switch from androgen-dependent to castration-resistant growth in prostate cancer.MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes.Germinal center kinases in immune regulation.Mammalian Hippo pathway: from development to cancer and beyond.Intersection of Hippo/YAP and Wnt/β-catenin signaling pathways.Dissecting Major Signaling Pathways throughout the Development of Prostate Cancer.The Hippo signal transduction network in skeletal and cardiac muscle.The non-canonical Hippo/Mst pathway in lymphocyte development and functions.A single acute pharmacological dose of γ-hydroxybutyrate modifies multiple gene expression patterns in rat hippocampus and frontal cortex.MST1: a promising therapeutic target to restore functional beta cell mass in diabetes.A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7.
P2860
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P2860
The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@ast
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en-gb
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@nl
type
label
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@ast
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en-gb
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@nl
prefLabel
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@ast
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en-gb
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@nl
P2093
P2860
P3181
P356
P1433
P1476
The pro-apoptotic kinase Mst1 ...... are direct inhibitors of Akt1
@en
P2093
Bekir Cinar
Dolores Di Vizio
Michael R Freeman
Mohini Lutchman
Natalya Pavlova
Pamela C Yelick
Ping-Ke Fang
Rosalyn M Adam
P2860
P304
P3181
P356
10.1038/SJ.EMBOJ.7601872
P407
P50
P577
2007-10-31T00:00:00Z