WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies
about
TCAB1: a potential target for diagnosis and therapy of head and neck carcinomasCharacteristics of Antisense Transcript Promoters and the Regulation of Their ActivitySignals controlling Cajal body assembly and functionCoilin: The first 25 yearsWRAP53 promotes cancer cell survival and is a potential target for cancer therapy.CTCF regulates the human p53 gene through direct interaction with its natural antisense transcript, Wrap53.Epstein-Barr virus-induced up-regulation of TCAB1 is involved in the DNA damage response in nasopharyngeal carcinoma.Telomerase Cajal body protein 1 depletion inhibits telomerase trafficking to telomeres and induces G1 cell cycle arrest in A549 cells.The role of nuclear bodies in gene expression and disease.On the road with WRAP53β: guardian of Cajal bodies and genome integrityThe Cajal body and the nucleolus: "In a relationship" or "It's complicated"?In vitro RNase and nucleic acid binding activities implicate coilin in U snRNA processingWRAP53 is an independent prognostic factor in rectal cancer- a study of Swedish clinical trial of preoperative radiotherapy in rectal cancer patients.Whole-genome screening identifies proteins localized to distinct nuclear bodiesThe scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repairTelomere-regulating genes and the telomere interactome in familial cancers.A pathophysiological view of the long non-coding RNA world.Regulation of neuronal differentiation by proteins associated with nuclear bodies.Overexpression of WRAP53 is associated with development and progression of esophageal squamous cell carcinomaCajal body proteins differentially affect the processing of box C/D scaRNPs.The Sub-Cellular Localization of WRAP53 Has Prognostic Impact in Breast CancerCYLD negatively regulates transforming growth factor-β-signalling via deubiquitinating AktMutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies.Telomerase recruitment requires both TCAB1 and Cajal bodies independently.Downregulation of the cancer susceptibility protein WRAP53β in epithelial ovarian cancer leads to defective DNA repair and poor clinical outcomeRegulated specific proteolysis of the Cajal body marker protein coilin.Coilin displays differential affinity for specific RNAs in vivo and is linked to telomerase RNA biogenesis.Cajal bodies are linked to genome conformationPhosphorylation regulates coilin activity and RNA associationSpectral imaging to visualize higher-order genomic organization.Overexpression of WDR79 in non-small cell lung cancer is linked to tumour progression.A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.Coilin association with Box C/D scaRNA suggests a direct role for the Cajal body marker protein in scaRNP biogenesis.Biogenesis of spliceosomal small nuclear ribonucleoproteins.Nuclear bodies: multifunctional companions of the genome.Cajal bodies: where form meets function.Regulatory RNPs: a novel class of ribonucleoproteins that potentially contribute to ribosome heterogeneity.Towards an understanding of regulating Cajal body activity by protein modification.The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1.SMN - A chaperone for nuclear RNP social occasions?
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P2860
WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@ast
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en-gb
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@nl
type
label
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@ast
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en-gb
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@nl
prefLabel
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@ast
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en-gb
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
WRAP53 is essential for Cajal ...... neuron complex to Cajal bodies
@en
P2093
Irene Weibrecht
Marianne Farnebo
Salah Mahmoudi
Sofia Henriksson
Stephen Smith
P2860
P304
P3181
P356
10.1371/JOURNAL.PBIO.1000521
P407
P577
2010-01-01T00:00:00Z