Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins. - Wikidata - awgldk - TriplyDB

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

http://www.wikidata.org/entity/Q24536283

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Development of a single vector system that enhances trans-splicing of SMN2 transcripts WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies Absence of gemin5 from SMN complexes in nuclear Cajal bodies Gemin8 is required for the architecture and function of the survival motor neuron complex Gle1 functions during mRNA export in an oligomeric complex that is altered in human disease NANOS1 and PUMILIO2 bind microRNA biogenesis factor GEMIN3, within chromatoid body in human germ cells Structure of a key intermediate of the SMN complex reveals Gemin2's crucial function in snRNP assembly Ongoing U snRNP biogenesis is required for the integrity of Cajal bodies Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins The survival motor neuron protein forms soluble glycine zipper oligomers The contribution of mouse models to understanding the pathogenesis of spinal muscular atrophy The Cajal body and histone locus body A SMN missense mutation complements SMN2 restoring snRNPs and rescuing SMA mice Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cgamma governs Cajal body localization and stability of the SMN complex A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila A stochastic view of spliceosome assembly and recycling in the nucleus Comparative Structural Analysis of Human DEAD-Box RNA Helicases Solution structure of the core SMN–Gemin2 complex DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function Dynamic control of Cajal body number during zebrafish embryogenesis.Molecular determinants of survival motor neuron (SMN) protein cleavage by the calcium-activated protease, calpain Ribonucleoprotein assembly defects correlate with spinal muscular atrophy severity and preferentially affect a subset of spliceosomal snRNPs Reduced viability, fertility and fecundity in mice lacking the cajal body marker protein, coilin.Genetic analysis of nuclear bodies: from nondeterministic chaos to deterministic order.Spinal Muscular Atrophy: From Defective Chaperoning of snRNP Assembly to Neuromuscular Dysfunction.Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?Spinal muscular atrophy: new and emerging insights from model mice The role of nuclear bodies in gene expression and disease.Diverse expression of selected SMN complex proteins in humans with sporadic amyotrophic lateral sclerosis and in a transgenic rat model of familial form of the disease.The Cajal body and the nucleolus: "In a relationship" or "It's complicated"?Quality control of assembly-defective U1 snRNAs by decapping and 5'-to-3' exonucleolytic digestion.DEAD-box helicase DP103 defines metastatic potential of human breast cancers.Conserved requirement for DEAD-box RNA helicase Gemin3 in Drosophila oogenesis RNA helicases in infection and disease.Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma.A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2.Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3).Depletion of SMN by RNA interference in HeLa cells induces defects in Cajal body formation.Nuclear bodies: random aggregates of sticky proteins or crucibles of macromolecular assembly?

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P2860

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

http://www.wikidata.org/entity/Q24536283

description

2005 nî lūn-bûn

@nan

2005 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

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2005年論文

@zh-tw

2005年论文

@wuu

name

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins

@nl

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@ast

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@en

type

label

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins

@nl

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@ast

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@en

prefLabel

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins

@nl

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@ast

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins.

@en

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PNAS.0508947102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins

@en

P2093

Karl B Shpargel

http://www.w3.org/2001/XMLSchema#string

P2860

Coupled in vitro import of U snRNPs and SMN, the spinal muscular atrophy protein

Interaction between the small-nuclear-RNA cap hypermethylase and the spinal muscular atrophy protein, survival of motor neuron

Self-association of coilin reveals a common theme in nuclear body localization

Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta

SMN tudor domain structure and its interaction with the Sm proteins

Essential role for the tudor domain of SMN in spliceosomal U snRNP assembly: implications for spinal muscular atrophy

The C-terminal RG dipeptide repeats of the spliceosomal Sm proteins D1 and D3 contain symmetrical dimethylarginines, which form a major B-cell epitope for anti-Sm autoantibodies

Spliceosomal UsnRNP biogenesis, structure and function

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17372-17377

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scholarly article

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10.1073/PNAS.0508947102

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P433

48

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102

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A. Gregory Matera

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2005-11-21T00:00:00Z

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7466327

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16301532

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ribonucleoprotein

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1297697

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