P185
Antiviral CD4+ memory T cells are IL-15 dependentATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytesPotent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cellsIL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor alpha subunit CD25The role of interleukin-2 during homeostasis and activation of the immune system.Breakdown in repression of IFN-γ mRNA leads to accumulation of self-reactive effector CD8+ T cells.Regulation of naïve and memory T-cell homeostasis.T cell memory.T memory cells: quality not quantity.Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models.Staying alive--naïve CD4(+) T cell homeostasis.Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}A fundamental role for interleukin-21 in the generation of T follicular helper cells.Cytokines and memory-phenotype CD8+ cells.Direct stimulation of T cells by membrane vesicles from antigen-presenting cells.Cytokines and T cell homeostasis.Turnover of memory-phenotype CD8+ T cells.Direct stimulation of naive T cells by membrane vesicles from antigen-presenting cells: distinct roles for CD54 and B7 moleculesIL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory.Swapping molecules during cell-cell interactions.Proving negative selection in the thymus.Regulation of mature T cell homeostasis.IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD.Direct stimulation of naïve T cells by antigen-presenting cell vesicles.A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells.An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2Overexpression of interleukin (IL)-7 leads to IL-15-independent generation of memory phenotype CD8+ T cellsInterleukin (IL)-15 and IL-7 jointly regulate homeostatic proliferation of memory phenotype CD8+ cells but are not required for memory phenotype CD4+ cells.Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection.Homeostasis of memory T cells.Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease.Cytokines and T-cell homeostasis.CD70-CD27 ligation between neural stem cells and CD4+ T cells induces Fas-FasL-mediated T-cell death.Self/non-self discrimination and the problem of keeping T cells alive.T cell homeostasis.Re-entry of mature T cells to the thymus: an epiphenomenon?In vivo expansion of T reg cells with IL-2-mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppressionHomeostasis of naive and memory T cells.Generation and maintenance of memory CD4(+) T Cells.CD45-mediated control of TCR tuning in naïve and memory CD8(+) T cells.
P50
Q24676283-EA70A7D9-584E-48AC-9E20-D0BE934658C5Q28591671-CF5C29CA-D6FB-435E-A7CD-C00BE0F3E0A9Q33705698-82E4B7BA-1919-498A-9658-43DC6A36F5C3Q33719745-2BEB8539-38E4-43F5-ABF3-3C21C114BB92Q34255232-9AF55074-4A64-41F1-95D5-8C849E2DAF4AQ34280390-5BF7CDDF-7F76-4BF0-B99A-559E5FD52BBAQ34515843-40003CF8-89D5-4B64-8E13-DC81FCE65F42Q34542272-2E4A2FE4-4416-41D2-97AA-311CB7EFF705Q34554239-547BFF01-7577-42FD-A5E7-D3566E759191Q34615453-C5EB9A83-A6BA-4B1C-9191-243B03A2C2CDQ34667935-1D2AF275-0C63-4CCA-BDE7-995BF9D979D8Q34694913-3E503B27-482E-424C-95FD-39BDFA648A5CQ34792475-290176B3-9CD7-4B0D-A6F4-0B58BE78E253Q34982873-F5C32831-2EF6-4B5F-8AD0-C5586D27BCE6Q34984478-94F626D4-6084-45C6-9768-2BC4A69DE0D9Q35044781-EFF36053-8925-4226-B342-AE486A53A07AQ35101811-F039F672-34D5-4FD5-A947-26B77FD79015Q35143903-BA92B1F4-1CBE-489B-8026-1C5206C86F60Q35319176-1E0396B4-51EE-4762-AF15-D11A20A8EE22Q36059242-4BCCBAD1-81B0-4F01-BE37-A36EE7E00953Q36075147-1E9A00B7-8281-4F53-95D0-3F3C66E4E50EQ36096534-1733183C-E4F7-49EB-819F-D5C3A596AF31Q36109177-B7B39380-C771-4C37-A17C-72B3BC3C90D7Q36149191-DB001DFC-930B-426B-8803-89DA58EC109CQ36228757-DEC28966-1C6D-490E-B0D1-E80D186F53EFQ36229586-FD7FA290-7EC5-453F-9880-B4288B04A110Q36369735-C0A6B25E-2C4A-463A-851E-3F8B44F715B9Q36369770-F1B4D620-79FA-4B3F-BA32-14F7BB28267DQ36402851-8E52AA37-9607-4A35-BA29-CCD120EF721EQ36528980-2BF229D8-7657-47A3-9FDE-C647CD270B60Q36708311-F1C61556-B30B-417A-8416-47AD76A8AF58Q36791437-0028F895-72C5-4D89-9758-4EAA51145A13Q36998531-9D81FDA5-C3A0-44A4-AA2D-FE59EAC0F59CQ37028785-CF38271B-D774-4451-BFEC-6046A609C7D8Q37117568-4BB26C57-E825-4CD6-9E11-DD337ED3930EQ37123626-45FBBD3A-F3AB-4D51-A160-E739809E6ADCQ37273329-18B3C451-AB9F-4020-AEEA-62C17F3509F2Q37356053-D128057A-097E-42EB-A9D4-8725D01D74BEQ37413769-F2F69D97-8D56-4C32-918D-67BA42213A2EQ37421679-D2468E42-B891-4AA7-8C77-BEB631E74949
P50
description
Australian immunologist
@en
immunoloog
@nl
name
Jonathan Sprent
@ast
Jonathan Sprent
@en
Jonathan Sprent
@es
Jonathan Sprent
@nl
type
label
Jonathan Sprent
@ast
Jonathan Sprent
@en
Jonathan Sprent
@es
Jonathan Sprent
@nl
prefLabel
Jonathan Sprent
@ast
Jonathan Sprent
@en
Jonathan Sprent
@es
Jonathan Sprent
@nl
P166
P1006
P214
P244
P1006
P106
P1153
7102085396
P166
P184
P19
P2070
jonathan-sprent-12332
P21
P213
0000 0003 9823 3082
P214
P244
P31
P735
P7859
lccn-n88095244