Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart - Wikidata - awgldk - TriplyDB

Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

http://www.wikidata.org/entity/Q21184170

about

Altered DNA methylation in leukocytes with trisomy 21 Concise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic disease Functional genomic analysis of amniotic fluid cell-free mRNA suggests that oxidative stress is significant in Down syndrome fetuses Evolution of the neocortex: a perspective from developmental biology Integrated analysis of DNA copy number and gene expression microarray data using gene sets Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome.Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomy Profiling expression changes caused by a segmental aneuploid in maize.Identification of dysregulated genes in lymphocytes from children with Down syndrome.Effects of aneuploidy on genome structure, expression, and interphase organization in Arabidopsis thaliana.Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.A critical period in cortical interneuron neurogenesis in down syndrome revealed by human neural progenitor cells.Using systems biology to simplify complex disease: immune cartography.Integrated analysis of gene expression and copy number data on gene shaving using independent component analysis Gene expression profiling in a mouse model identifies fetal liver- and placenta-derived potential biomarkers for Down Syndrome screening.Ohnologs in the human genome are dosage balanced and frequently associated with disease.Brain phenotype of transgenic mice overexpressing cystathionine β-synthase.The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.Noninvasive prenatal testing creates an opportunity for antenatal treatment of Down syndrome.Molecular signatures of cardiac defects in Down syndrome lymphoblastoid cell lines suggest altered ciliome and Hedgehog pathways.Genome-wide expression analysis in Down syndrome: insight into immunodeficiency.Potential contribution of SIM2 and ETS2 functional polymorphisms in Down syndrome associated malignancies.Expression signature as a biomarker for prenatal diagnosis of trisomy 21.Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes.Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and death.Explore the dynamic alternation of gene PLAC4 mRNA expression levels in maternal plasma in second trimester for nonivasive detection of trisomy 21 Gene expression variation in Down's syndrome mice allows prioritization of candidate genes Natural gene-expression variation in Down syndrome modulates the outcome of gene-dosage imbalance Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes The power of comparative and developmental studies for mouse models of Down syndrome Molecular and cellular alterations in Down syndrome: toward the identification of targets for therapeutics Transcriptional consequences of aneuploidy.Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination.Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome.Validation of computational methods in genomics.Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy An Integrated Human/Murine Transcriptome and Pathway Approach To Identify Prenatal Treatments For Down Syndrome.Trisomy 21 and Down syndrome: a short review.

P2860

Q21144966-4CF818CB-ECD0-4170-86EE-D096BF6EBA67 Q22241147-458FEDB3-6A62-4DA9-9A5B-9C4B844A0A08 Q24654648-53BAB63F-196C-42B8-8B6A-CF8797C2354D Q28258984-78EBEB47-6B81-4F4A-9211-2914D979498F Q30490621-EEAAC953-0CC8-4BFE-B765-DC5B9F448B7E Q30653697-46A07F94-E272-4C91-A5A3-B72EB3464754 Q33236637-165F1855-6374-4D13-A894-8EBE8195C692 Q33293466-B6289C31-CBF5-412C-99D0-D02A3439BEC6 Q33314156-51227C23-426E-4740-8270-1362BDCD36A8 Q33324833-612492B9-7A3A-4EBA-9921-4EB9B2196600 Q33377464-A830C6CA-B0CC-4862-9100-7B939BEC9CF7 Q33424071-FEA134DB-B832-4F42-AC50-B48BD884F30E Q33637811-2B85B23E-1EBB-4AEF-AEE7-73D4CABB8E5E Q33828840-2BA1E9D5-2119-40D1-AB69-DCBE03778921 Q33881798-2D7E6371-8473-4D16-B091-C5700EA87D2B Q33886427-8412356B-7E98-45BE-AE7D-2E57898FDF1C Q33927314-A3C98D30-C03F-42D9-80FD-77EC546A01C6 Q34130338-43DE7112-2338-4F1E-BB84-560BA6CFDA72 Q34302163-909563C7-F72A-46A8-9710-423533B5E995 Q34339997-C740A693-9C84-4CFF-98E0-C3EBA35F16F6 Q34388617-205F7829-F8A8-4F60-AFF5-C731A199FF6D Q34479257-786F27AF-4AEF-4F57-A9C5-50005023D2B6 Q34560086-10A90860-68AE-4315-A142-97A0D8FF23DC Q34997264-108666CF-D72F-44AE-9AEE-05C3037684DF Q35101795-BCBCB716-1C45-448C-A5FE-85142516482E Q35863933-599C22D1-74D8-4236-9503-5776BBED1117 Q35890325-8E354E25-34B5-4406-8FE1-DECADC6CD895 Q35906498-4E4DA5B1-4428-48E1-BC72-DD403755B3FB Q35946259-79F88568-FF5C-4434-957B-12594A003CC4 Q35946317-BC83A536-8780-4E22-8F88-E5DE4F5E05E2 Q36021399-EDA7C5D9-A918-4D93-921C-90B5AD6D73C6 Q36111546-7EDCD748-CF12-43B4-B8FD-831C14B13A67 Q36140289-8C13375A-7BCE-4FC3-B92F-F8A81EF65825 Q36698095-164DCDD3-666F-440E-8952-DC86E27C0446 Q36767282-4F304691-63B3-4AC8-B519-571DBC626417 Q36775869-1C49DCB4-0993-4585-B31C-79B525D5668D Q36873757-7D855162-EC5F-454A-A0B2-475B1D34C05D Q36992082-0C9E672D-22FF-4941-A47B-5A4C0B6E2B11 Q37228171-B3AC9A4C-A3AD-4E5E-A58A-CCF192D8A164 Q37228422-C54D40AA-71FD-4493-9302-5DA57D2DF3CB

P2860

Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart

http://www.wikidata.org/entity/Q21184170

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Primary and secondary transcri ...... Down syndrome brain and heart

@ast

Primary and secondary transcri ...... Down syndrome brain and heart

@en

Primary and secondary transcri ...... Down syndrome brain and heart

@en-gb

Primary and secondary transcri ...... Down syndrome brain and heart

@nl

type

label

Primary and secondary transcri ...... Down syndrome brain and heart

@ast

Primary and secondary transcri ...... Down syndrome brain and heart

@en

Primary and secondary transcri ...... Down syndrome brain and heart

@en-gb

Primary and secondary transcri ...... Down syndrome brain and heart

@nl

prefLabel

Primary and secondary transcri ...... Down syndrome brain and heart

@ast

Primary and secondary transcri ...... Down syndrome brain and heart

@en

Primary and secondary transcri ...... Down syndrome brain and heart

@en-gb

Primary and secondary transcri ...... Down syndrome brain and heart

@nl

P1433

Q21184170-2FD9816F-BFAA-47D4-9575-107542EDE7C3

P1476

Q21184170-47D4E000-3576-4ECB-BBC2-7418BC772532

P2093

Q21184170-1069A0E7-B208-4F4D-B7DF-B3943CDDC51F

Q21184170-23F4E583-A533-4501-AC3E-DE34FA331479

Q21184170-348E09EA-6FD5-438F-AFBF-C1EB3DFD960F

Q21184170-53CAA2D4-336E-48C9-8FFF-AC38407A50D4

Q21184170-638B3661-C12C-4F8E-BA42-437277C69046

Q21184170-70DE8F8A-6A93-48F9-A820-027ADE95119A

Q21184170-7CDB6973-8501-421D-BDA1-2DF2D52EF7D5

Q21184170-91482F98-619B-4927-9BE2-CC495653E4AA

Q21184170-D5479BB1-B5FF-4E17-9A54-F7E1E954D7F1

Q21184170-E9CDAC90-C156-423E-BB3C-AD2E2F744C60

P2860

Q21184170-0E7BC45D-7F6E-45C3-835B-2CF103737B26

Q21184170-1408A1FD-6A8C-465F-A11E-14897FF8C963

Q21184170-1B3A7004-55B8-49D9-A57D-8BA3AC0CF78C

Q21184170-1F014CB2-48D0-475D-BCCE-6573A704C051

Q21184170-23056322-D625-474C-B827-8C62CC363F8F

Q21184170-2768ACCA-DCF7-416C-B388-846248E8AAEE

Q21184170-29288885-64C0-428E-81F4-266018C53943

Q21184170-30D4A4E1-B267-43EC-ADCB-9009F4AF30A8

Q21184170-3790EAD1-44F0-4A51-BAB8-A0DCCC81178E

Q21184170-39EA1D03-814A-45DF-9384-1E45BC025FF1

P2888

Q21184170-EFDC0F6B-851A-4B91-A1E0-33FEEA878679

P304

Q21184170-E0C20038-AD08-4A78-BDF3-6CCBFF3E4E28

P31

Q21184170-835391EF-77C1-437C-93EB-CB66E401252D

P3181

Q21184170-6D5FE8F4-1D9D-4C9B-913F-8CA61B0BDA83

P356

Q21184170-DF0097F7-619B-4A19-B657-0DF329060EE7

P407

Q21184170-8CD420A4-C930-451A-B324-2C5F19C1FD42

P433

Q21184170-80D0D2BD-7BFB-44C9-96E8-C5AA2DCE71FA

P478

Q21184170-0E61A5E8-FFF1-4493-9F60-ED30594D73B3

P50

Q21184170-39B32602-7120-4FCC-862E-52C2402BFBB4

Q21184170-5B5FF1FA-DB01-4921-9B5D-374CEC766B66

P577

Q21184170-BBFD8DEA-4C9E-40E7-9B41-3AD52F216873

P5875

Q21184170-9782B769-8140-4986-B012-283B7631FDE1

P698

Q21184170-7CA0DF81-6C8A-49B8-A585-EBE0D92111A3

P921

Q21184170-D7D86DA7-772A-418B-8D7C-FF3CC7D115D8

P932

Q21184170-DCBF5B2B-A84C-4D77-B69A-4F7E8E9B8A22

P3181

P356

GB-2005-6-13-R107

P1433

P1476

Primary and secondary transcri ...... Down syndrome brain and heart

@en

P2093

Edward L Spitznagel

http://www.w3.org/2001/XMLSchema#string

Huashi Ding

http://www.w3.org/2001/XMLSchema#string

Ingo Ruczinski

http://www.w3.org/2001/XMLSchema#string

Jason C Ting

http://www.w3.org/2001/XMLSchema#string

Jonathan Pevsner

http://www.w3.org/2001/XMLSchema#string

Jung-whan Kim

http://www.w3.org/2001/XMLSchema#string

Laurence P Frelin

http://www.w3.org/2001/XMLSchema#string

Rong Mao

http://www.w3.org/2001/XMLSchema#string

Thomas J Downey

http://www.w3.org/2001/XMLSchema#string

Xiaowen Wang

http://www.w3.org/2001/XMLSchema#string

P2860

Gene ontology: tool for the unification of biology

GoMiner: a resource for biological interpretation of genomic and proteomic data

GOTree Machine (GOTM): a web-based platform for interpreting sets of interesting genes using Gene Ontology hierarchies

MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data

Dosage balance in gene regulation: biological implications

The Gene Ontology (GO) database and informatics resource

Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain

Expression of type VI collagen in the developing mouse heart

Diagnosis of multiple cancer types by shrunken centroids of gene expression

GO::TermFinder--open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes

P2888

gb-2005-6-13-r107

P304

R107

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3703095

http://www.w3.org/2001/XMLSchema#string

P356

10.1186/GB-2005-6-13-R107

http://www.w3.org/2001/XMLSchema#string

P407

P433

13

http://www.w3.org/2001/XMLSchema#string

P478

6

http://www.w3.org/2001/XMLSchema#string

P50

Jonathan Pevsner

P577

2005-12-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7351289

http://www.w3.org/2001/XMLSchema#string

P698

16420667

http://www.w3.org/2001/XMLSchema#string

P921

P932

1414106

http://www.w3.org/2001/XMLSchema#string