Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
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Primary and secondary transcriptional effects in the developing human Down syndrome brain and heartGene-dosage effects in Down syndrome and trisomic mouse modelsConcise review: new paradigms for Down syndrome research using induced pluripotent stem cells: tackling complex human genetic diseaseThe cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor proteinAneuploidy: cells losing their balanceAneuploidy affects proliferation and spontaneous immortalization in mammalian cellsComparison of array-based comparative genomic hybridization with gene expression-based regional expression biases to identify genetic abnormalities in hepatocellular carcinomaThe consequences of chromosomal aneuploidy on the transcriptome of cancer cellsChromosome 21 and down syndrome: from genomics to pathophysiologyCharacterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTBDyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1.Validation of microarray data in human lymphoblasts shows a role of the ubiquitin-proteasome system and NF-kB in the pathogenesis of Down syndrome.Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21.Understanding the basis for Down syndrome phenotypes.Genetic basis for dosage sensitivity in Arabidopsis thaliana.Altered expression of mitochondrial and extracellular matrix genes in the heart of human fetuses with chromosome 21 trisomyProfiling expression changes caused by a segmental aneuploid in maize.Identification of dysregulated genes in lymphocytes from children with Down syndrome.Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development.Matrix factorisation methods applied in microarray data analysisChromosome 21-derived microRNAs provide an etiological basis for aberrant protein expression in human Down syndrome brains.Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma.A critical period in cortical interneuron neurogenesis in down syndrome revealed by human neural progenitor cells.Massive-scale RNA-Seq analysis of non ribosomal transcriptome in human trisomy 21.Meta-analysis of heterogeneous Down Syndrome data reveals consistent genome-wide dosage effects related to neurological processesSegmental trisomy of chromosome 17: a mouse model of human aneuploidy syndromesFunctional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networksChromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression.Complex genomic alterations and gene expression in acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21.Global DNA hypermethylation in down syndrome placentaHuman chromosome 21-derived miRNAs are overexpressed in down syndrome brains and hearts.Gene expression analysis of induced pluripotent stem cells from aneuploid chromosomal syndromes.Human neural stem cells: a new tool for studying cortical development in Down's syndrome.Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndromeGene expression from the aneuploid chromosome in a trisomy mouse model of down syndromeNoncoding RNAs in mental retardation
P2860
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P2860
Global up-regulation of chromosome 21 gene expression in the developing Down syndrome brain
description
2003 nî lūn-bûn
@nan
2003 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Global up-regulation of chromo ...... developing Down syndrome brain
@ast
Global up-regulation of chromo ...... developing Down syndrome brain
@en
Global up-regulation of chromo ...... developing Down syndrome brain
@nl
type
label
Global up-regulation of chromo ...... developing Down syndrome brain
@ast
Global up-regulation of chromo ...... developing Down syndrome brain
@en
Global up-regulation of chromo ...... developing Down syndrome brain
@nl
prefLabel
Global up-regulation of chromo ...... developing Down syndrome brain
@ast
Global up-regulation of chromo ...... developing Down syndrome brain
@en
Global up-regulation of chromo ...... developing Down syndrome brain
@nl
P2093
P3181
P1433
P1476
Global up-regulation of chromo ...... developing Down syndrome brain
@en
P2093
Carol L Zielke
H Ronald Zielke
P304
P3181
P356
10.1016/S0888-7543(03)00035-1
P407
P577
2003-05-01T00:00:00Z