Diffusion-driven looping provides a consistent framework for chromatin organization
about
High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division.Entropy gives rise to topologically associating domains.The role of loops on the order of eukaryotes and prokaryotesPhysical mechanisms behind the large scale features of chromatin organizationCHiCAGO: robust detection of DNA looping interactions in Capture Hi-C dataUnderstanding spatial organizations of chromosomes via statistical analysis of Hi-C dataThe sequencing bias relaxed characteristics of Hi-C derived data and implications for chromatin 3D modelingTransient chromatin properties revealed by polymer models and stochastic simulations constructed from Chromosomal Capture data.Repulsive forces between looping chromosomes induce entropy-driven segregationEvolution of histone 2A for chromatin compaction in eukaryotes.Spatial confinement is a major determinant of the folding landscape of human chromosomes.Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains.Loops determine the mechanical properties of mitotic chromosomes.Nipbl and mediator cooperatively regulate gene expression to control limb development.Expression-dependent folding of interphase chromatinDepletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction: insight into chromatin folding by polymer modellingExploring the three-dimensional organization of genomes: interpreting chromatin interaction data.Modeling and experimental methods to probe the link between global transcription and spatial organization of chromosomes.The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments.Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans.Inferential modeling of 3D chromatin structureTopology, structures, and energy landscapes of human chromosomes.Perspectives: using polymer modeling to understand the formation and function of nuclear compartments.A fractal model for nuclear organization: current evidence and biological implications.Complexity of chromatin folding is captured by the strings and binders switch model.Using chimaeric expression sequence tag as the reference to identify three-dimensional chromosome contactsPolymer models of chromatin organizationFormation of Chromosomal Domains by Loop Extrusion.Polymer physics of chromosome large-scale 3D organisationThe hierarchy of the 3D genome.A polymer model explains the complexity of large-scale chromatin folding.Chromosome positioning from activity-based segregation.Chromatin globules: a common motif of higher order chromosome structure?Compartmentalization of the nucleus.Modeling chromosomes: Beyond pretty pictures.Physical properties of the chromosomes and implications for development.Loss of lamin A function increases chromatin dynamics in the nuclear interior.Predicting chromatin architecture from models of polymer physics.Modelling of cell killing due to sparsely ionizing radiation in normoxic and hypoxic conditions and an extension to high LET radiation.Current theoretical models fail to predict the topological complexity of the human genome.
P2860
Q27318586-3E2D240D-28EF-4A59-9550-6373647AD6E0Q27323070-0CB3CBBA-1D37-46D4-8723-2884CA5FFB9FQ28081349-92ABA948-872A-4078-93BE-8E3A84BE160BQ28086968-99DD263B-A808-4AC0-9217-EAFE75FE1F86Q28601222-B553A696-6B63-4711-971A-7F213B1794C7Q28647858-6BC8CCEA-7157-459E-9453-94C953041D2AQ30662716-4895BE47-20A7-4461-90B8-5934CEB34ADAQ33570971-FA47F3EA-9657-414D-8E55-3932B2FCE252Q33796502-C7D76C8D-949F-4427-BD60-D7B335860946Q33901516-C626310A-C7C4-4CA1-95B7-3C3FAD6E9D69Q33983460-94EFC897-33E9-458D-A7FB-7127529A839BQ34115510-714B90D6-475B-4DFD-973A-1A34624D99E4Q34117373-7445CE9E-D990-48F9-B55C-6DCA0A2C641CQ34256743-0FF579B7-7A52-49C5-84CB-68F273CB425FQ34287511-42A3C87F-C1BC-41C7-96D4-8E9DF457D2B0Q34314868-61320C97-9B8E-42CF-AAEE-CF1ED8DC96E5Q34343663-7645B9B2-670A-4F3D-8B68-C075B141A238Q34437709-2954FFEB-F95E-4867-9035-30F727CAB1B2Q34478652-49E78BDE-7B74-4134-8D6D-0E01E394230EQ34590236-821F75B9-F630-4F06-9877-65EF9EA27E9CQ35562032-F4372158-3773-4DF9-8D5D-70CC1D14DA09Q35616170-3FD1B84A-9A7A-48D7-95A8-9794FF34DCBEQ36250466-71466FEB-DDE4-4702-BF7B-E0FE1DE393E3Q36305576-F7B5EB57-126D-4DFE-8489-57AC1611B537Q36342953-DE77A1CB-13DA-47AC-9EA8-0B88C400FEC2Q36622254-4AA47C3D-6CE2-431D-A0CC-478AD36A65C8Q36941824-BFB6256D-25A0-451D-99FC-A5B8B47D58CCQ36957773-2B724FD0-73D7-41D2-A0A6-F5211290240EQ37089711-B8A2D31A-5D23-4C65-AF55-8EB133D7A2B4Q37090603-B6AE88EE-4530-470B-A4EE-386644FC117BQ37260933-3EB9AB8B-7B91-4685-A5FE-808FC53359FAQ37701278-15D0DD85-D25A-4417-91C7-B25B39A3E6D2Q37864798-E8277614-0F66-47F2-A054-8A37113B3BFEQ37928797-5FD1FC35-BE71-4A55-B813-DC124D3D711EQ38585877-1A4C4939-814E-49CD-A5F9-BFB69550BC37Q38675814-13125074-344C-4DAA-B18F-57A3FE5CBF8FQ38841598-CB64A218-F316-4369-AA61-D4A51B108605Q39030113-37FD5009-AF79-4155-B965-943EC96D6AE2Q39158692-AA20787A-063A-4A81-9AF1-CE10C22C6F44Q40564179-4CDEF27B-D504-4265-B960-736369FB1CD0
P2860
Diffusion-driven looping provides a consistent framework for chromatin organization
description
2010 nî lūn-bûn
@nan
2010 թուականին հրատարակուած գիտական յօդուած
@hyw
2010 թվականին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Diffusion-driven looping provides a consistent framework for chromatin organization
@ast
Diffusion-driven looping provides a consistent framework for chromatin organization
@en
Diffusion-driven looping provides a consistent framework for chromatin organization
@en-gb
Diffusion-driven looping provides a consistent framework for chromatin organization
@nl
type
label
Diffusion-driven looping provides a consistent framework for chromatin organization
@ast
Diffusion-driven looping provides a consistent framework for chromatin organization
@en
Diffusion-driven looping provides a consistent framework for chromatin organization
@en-gb
Diffusion-driven looping provides a consistent framework for chromatin organization
@nl
altLabel
Diffusion-Driven Looping Provides a Consistent Framework for Chromatin Organization
@en
prefLabel
Diffusion-driven looping provides a consistent framework for chromatin organization
@ast
Diffusion-driven looping provides a consistent framework for chromatin organization
@en
Diffusion-driven looping provides a consistent framework for chromatin organization
@en-gb
Diffusion-driven looping provides a consistent framework for chromatin organization
@nl
P2860
P3181
P1433
P1476
Diffusion-driven looping provides a consistent framework for chromatin organization
@en
P2093
Dieter W Heermann
Manfred Bohn
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0012218
P407
P577
2010-01-01T00:00:00Z