Complexity of chromatin folding is captured by the strings and binders switch model.
about
A simple biophysical model emulates budding yeast chromosome condensationFractal dimension of chromatin: potential molecular diagnostic applications for cancer prognosisHigh resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division.Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains.Simulated binding of transcription factors to active and inactive regions folds human chromosomes into loops, rosettes and topological domains.Chromatin topology is coupled to Polycomb group protein subnuclear organization.Predicting the three-dimensional folding of cis-regulatory regions in mammalian genomes using bioinformatic data and polymer modelsProtein/DNA interactions in complex DNA topologies: expect the unexpectedThe role of loops on the order of eukaryotes and prokaryotesOn the demultiplexing of chromosome capture conformation dataPhysical mechanisms behind the large scale features of chromatin organizationInferential Structure Determination of Chromosomes from Single-Cell Hi-C DataUnderstanding spatial organizations of chromosomes via statistical analysis of Hi-C dataNonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization.High-quality genome (re)assembly using chromosomal contact data.Transposable Elements and DNA Methylation Create in Embryonic Stem Cells Human-Specific Regulatory Sequences Associated with Distal Enhancers and Noncoding RNAsThe sequencing bias relaxed characteristics of Hi-C derived data and implications for chromatin 3D modelingHi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization.The detailed 3D multi-loop aggregate/rosette chromatin architecture and functional dynamic organization of the human and mouse genomes.Hierarchical block matrices as efficient representations of chromosome topologies and their application for 3C data integration.Transient chromatin properties revealed by polymer models and stochastic simulations constructed from Chromosomal Capture data.Global genetic response in a cancer cell: self-organized coherent expression dynamics.Dynamic chromatin accessibility modeled by Markov process of randomly-moving molecules in the 3D genomeSpatial confinement is a major determinant of the folding landscape of human chromosomes.Modeling epigenome folding: formation and dynamics of topologically associated chromatin domains.Depletion of the chromatin looping proteins CTCF and cohesin causes chromatin compaction: insight into chromatin folding by polymer modellingExploring the three-dimensional organization of genomes: interpreting chromatin interaction data.Three-dimensional genome architecture: players and mechanisms.The 4D nucleome: Evidence for a dynamic nuclear landscape based on co-aligned active and inactive nuclear compartments.Estrogen induces global reorganization of chromatin structure in human breast cancer cellsSingle-cell states in the estrogen response of breast cancer cell linesClustering of mammalian Hox genes with other H3K27me3 targets within an active nuclear domain.Topology, structures, and energy landscapes of human chromosomes.Emergent Self-Organized Criticality in Gene Expression Dynamics: Temporal Development of Global Phase Transition Revealed in a Cancer Cell Line.Distinct polymer physics principles govern chromatin dynamics in mouse and Drosophila topological domainsThe chromatin fiber: multiscale problems and approaches.Large Scale Chromosome Folding Is Stable against Local Changes in Chromatin Structure.Dynamic Nucleosome Movement Provides Structural Information of Topological Chromatin Domains in Living Human Cells.A Looping-Based Model for Quenching Repression.Perspectives: using polymer modeling to understand the formation and function of nuclear compartments.
P2860
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P2860
Complexity of chromatin folding is captured by the strings and binders switch model.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Complexity of chromatin folding is captured by the strings and binders switch model.
@ast
Complexity of chromatin folding is captured by the strings and binders switch model.
@en
type
label
Complexity of chromatin folding is captured by the strings and binders switch model.
@ast
Complexity of chromatin folding is captured by the strings and binders switch model.
@en
prefLabel
Complexity of chromatin folding is captured by the strings and binders switch model.
@ast
Complexity of chromatin folding is captured by the strings and binders switch model.
@en
P2093
P2860
P356
P1476
Complexity of chromatin folding is captured by the strings and binders switch model.
@en
P2093
James Fraser
Josée Dostie
Liron-Mark Lavitas
Mariano Barbieri
Mita Chotalia
P2860
P304
16173-16178
P356
10.1073/PNAS.1204799109
P407
P577
2012-09-17T00:00:00Z