Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
about
Transporting mitochondria in neuronsRegulation of mitochondrial functions by protein phosphorylation and dephosphorylationAlterations in Mitochondrial Quality Control in Alzheimer's DiseaseMitochondria-associated membranes as hubs for neurodegenerationMIRO GTPases in Mitochondrial Transport, Homeostasis and PathologyRBR E3 ubiquitin ligases: new structures, new insights, new questionsMouse models of Parkinson's disease associated with mitochondrial dysfunctionEmerging modes of PINK1 signaling: another task for MARK2Methods for studying planar cell polarityPINK1-mediated phosphorylation of Parkin boosts Parkin activity in DrosophilaTissue- and cell-specific mitochondrial defect in Parkin-deficient miceHuman A53T α-synuclein causes reversible deficits in mitochondrial function and dynamics in primary mouse cortical neuronsStructural coupling of the EF hand and C-terminal GTPase domains in the mitochondrial protein MiroEvidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1Mitochondrial trafficking in neuronsMitochondrial dynamics and mitochondrial quality controlGlutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagyBeyond mitophagy: cytosolic PINK1 as a messenger of mitochondrial healthParkin-mediated mitophagy in mutant hAPP neurons and Alzheimer's disease patient brainsMacroautophagy and cell responses related to mitochondrial dysfunction, lipid metabolism and unconventional secretion of proteinsMorphological and bioenergetic demands underlying the mitophagy in post-mitotic neurons: the pink-parkin pathwayVimar Is a Novel Regulator of Mitochondrial Fission through MiroStructural insights into Parkin substrate lysine targeting from minimal Miro substratesNeuronal Mitophagy in Neurodegenerative DiseasesLandscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarizationPINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65Axon degeneration and PGC-1α-mediated protection in a zebrafish model of α-synuclein toxicityIncreasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations.PINK1-mediated phosphorylation of Miro inhibits synaptic growth and protects dopaminergic neurons in DrosophilaMitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease.Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligaseCutaneous neuropathy in Parkinson's disease: a window into brain pathology.New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders.The mitochondrial Ras-related GTPase Miro: views from inside and outside the metazoan kingdom.Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease.Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.Mitochondrial quality control mediated by PINK1 and Parkin: links to parkinsonism.The pallidopyramidal syndromes: nosology, aetiology and pathogenesis.Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through protein kinase ALoss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1.
P2860
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P2860
Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Parkinson's disease-associated ...... onal transport of mitochondria
@ast
Parkinson's disease-associated ...... onal transport of mitochondria
@en
Parkinson's disease-associated ...... onal transport of mitochondria
@en-gb
Parkinson's disease-associated ...... onal transport of mitochondria
@nl
type
label
Parkinson's disease-associated ...... onal transport of mitochondria
@ast
Parkinson's disease-associated ...... onal transport of mitochondria
@en
Parkinson's disease-associated ...... onal transport of mitochondria
@en-gb
Parkinson's disease-associated ...... onal transport of mitochondria
@nl
altLabel
Parkinson's Disease–Associated ...... onal Transport of Mitochondria
@en
prefLabel
Parkinson's disease-associated ...... onal transport of mitochondria
@ast
Parkinson's disease-associated ...... onal transport of mitochondria
@en
Parkinson's disease-associated ...... onal transport of mitochondria
@en-gb
Parkinson's disease-associated ...... onal transport of mitochondria
@nl
P2093
P2860
P3181
P1433
P1476
Parkinson's disease-associated ...... onal transport of mitochondria
@en
P2093
Alice Shen
Bingwei Lu
George Silverio
Ivan Millan
Philomena Alapatt
Ryosuke Takahashi
Seongsoo Lee
Tomoko Kanao
Tomoyo Sawada
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1002537
P407
P577
2012-01-01T00:00:00Z