about
P688
The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors.Downregulation of Fer induces PP1 activation and cell-cycle arrest in malignant cellsFer is a downstream effector of insulin and mediates the activation of signal transducer and activator of transcription 3 in myogenic cellsFer-mediated cortactin phosphorylation is associated with efficient fibroblast migration and is dependent on reactive oxygen species generation during integrin-mediated cell adhesionThe protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinaseAbsence of Fer protein tyrosine kinase exacerbates endotoxin induced intestinal epithelial barrier dysfunction in vivoPhosphorylation of N-cadherin-associated cortactin by Fer kinase regulates N-cadherin mobility and intercellular adhesion strength.Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activationFer kinase is required for sustained p38 kinase activation and maximal chemotaxis of activated mast cells
P921
Q24320101-ED4113D1-FB74-443E-8680-FB9BCB1E4B0EQ24338283-041D9076-7B11-494F-90A5-0154A4D2B834Q28505028-0CD2571E-62BC-4C7F-B425-EFBAAE65A9E3Q28510183-DB04221E-19F3-4487-A26B-3ACEB656657BQ28511001-3D14F7D7-5BBB-4DBF-8E56-0F8C52305AC1Q28512899-BE806545-2E48-4261-A63B-6A73EC173B5FQ28513480-9629D411-C090-48FC-AAAA-F90FC6F6EE90Q28590899-1A2C3A3B-0085-4A73-AE7D-B68B6A9DC344Q28593250-FF1988C6-26A9-4FB5-A435-E75EA069882A
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Fer (fms/fps related) protein kinase
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Fer (fms/fps related) protein kinase
@en
Fer
@nl
type
label
Fer (fms/fps related) protein kinase
@en
Fer
@nl
altLabel
Fer
@en
fer (fms/fps related) protein kinase, testis specific 2
@en
p94-Fer
@en
proto-oncogene c-Fer
@en
proto-oncogene tyrosine-protein kinase Fer
@en
tyrosine-protein kinase Fer
@en
prefLabel
Fer (fms/fps related) protein kinase
@en
Fer
@nl
P361
P527
P637
P680
P681
P682
P352
P637
P31
P352
P361
P527
P637
NP_001033086
NP_001273344
XP_006523703
XP_006523704
XP_006523706
XP_006523708
XP_006523710
XP_006523712
XP_006523713
P680
P681
P682
P702
P703
P705
ENSMUSP00000000129
ENSMUSP00000037418