The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase
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Closing in on the biological functions of Fps/Fes and FerFER tyrosine kinase (FER) overexpression mediates resistance to quinacrine through EGF-dependent activation of NF-kappaBIntegrative analysis of high-throughput RNAi screen data identifies the FER and CRKL tyrosine kinases as new regulators of the mitogenic ERK-dependent pathways in transformed cellsThe Novel Functions of High-Molecular-Mass Complexes Containing Insulin Receptor Substrates in Mediation and Modulation of Insulin-Like Activities: Emerging Concept of Diverse Functions by IRS-Associated ProteinsThe Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo.Fer kinase limits neutrophil chemotaxis toward end target chemoattractants.Gamma interferon down-regulates Fer and induces its association with inactive Stat3 in colon carcinoma cells.Amplified Ras-MAPK signal states correlate with accelerated EGFR internalization, cytostasis and delayed HER2 tumor onset in Fer-deficient model systems.
P2860
Q24296817-53743F27-4B9E-4636-8097-831398A08B7CQ24300387-49B9D7CA-3E85-4868-901C-900FEEB1B913Q24311542-B8D891BF-83AF-4D03-AE0C-D665A56C66FFQ28088661-7BA2ECC6-9EE7-47C3-91E4-7BD5ABA8B476Q39165746-2E4C308D-105D-4CC5-9296-0D72FFFB0C9FQ43245209-61304666-67C6-4657-803A-6C7804465C20Q44064309-43663175-364F-4EC2-AE2D-19E8238C53DDQ51020126-96FDACEA-755F-4AC6-9F38-59F9B3A00D55
P2860
The protein-tyrosine kinase fer associates with signaling complexes containing insulin receptor substrate-1 and phosphatidylinositol 3-kinase
description
2000 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2000
@ast
im Dezember 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/12/15)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/12/15)
@nl
наукова стаття, опублікована в грудні 2000
@uk
name
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@ast
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@en
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@nl
type
label
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@ast
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@en
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@nl
prefLabel
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@ast
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@en
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@nl
P2093
P2860
P356
P1476
The protein-tyrosine kinase fe ...... phosphatidylinositol 3-kinase
@en
P2093
A. D. Cherniack
M. Iwanishi
M. P. Czech
P2860
P304
38995–39000
P356
10.1074/JBC.M006665200
P407
P577
2000-12-15T00:00:00Z