about
P688
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophagesInsect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFNInvolvement of heat shock protein (Hsp)90 beta but not Hsp90 alpha in antiapoptotic effect of CpG-B oligodeoxynucleotideNucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitisExtensive characterization of IFN-induced GTPases mGBP1 to mGBP10 involved in host defenseInterferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 inductionLocalization of pro-inflammatory (IL-12, IL-15) and anti-inflammatory (IL-11, IL-13) cytokines at the foetomaternal interface during murine pregnancyPellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitisH-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunityNegative regulation of Toll-like-receptor signaling by IRF-4.Nod2-dependent regulation of innate and adaptive immunity in the intestinal tractNOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responsesInterleukin-12 enhances interleukin-3 dependent multilineage hematopoietic colony formation stimulated by interleukin-11 or steel factorIL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunizationRecognition of Toxoplasma gondii by TLR11 prevents parasite-induced immunopathologyGlucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activationDevelopment of Th1-type immune responses requires the type I cytokine receptor TCCRRole of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathwayCD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response developmentShared dependence on the DNA-binding factor TOX for the development of lymphoid tissue-inducer cell and NK cell lineages.
P921
Q24290619-EB535326-3DBA-49AD-84F7-38E5AEF8C3D7Q28506067-2EA294CA-FAB1-4840-9C7E-7167E18D23CDQ28508268-8FE6E825-CABD-4566-93D0-4DB870B6ECBEQ28509007-E16C8E6B-EC9F-438F-8E4B-85A64BE31BA1Q28511027-E4F3C3D1-CBB4-4FD8-96E7-5BEB90CA4754Q28512319-E3AE496D-EFDC-4091-926D-8174FC6292BAQ28513103-5BE8AD16-B01E-42AA-B48F-AA2ACC81783DQ28513378-184F703A-9BD4-44B7-9C77-D8CD0DAC4AECQ28513622-1AAD9DFB-42A5-4502-BC4A-75236890E4C3Q28586754-23793EA0-6AE7-4368-A5D5-6BC99D0F8BD3Q28587563-8E60C3E2-A8F5-42C6-AC04-5ACC0EC78188Q28587612-48ACAF23-580C-467F-AF05-CB40644E37CFQ28588300-5E883602-9427-44EE-935F-03BC8C684255Q28588956-884312E5-589F-4410-938D-F55290563394Q28589035-F62A7D14-66AD-4BFF-AD09-3986B0D6760DQ28589947-93338E1B-EA2C-4B88-BF66-3FE0850C50CDQ28590220-EF73B477-2951-4FB6-BAF6-8AA8DB98EB11Q28591931-456B233E-B1FA-426F-8531-C43382388B92Q28592087-CB07C2DB-1D5A-4C2F-B582-5669CC7D2FFDQ28594824-FC1B584E-9342-4D94-AD0C-633146F6EA3FQ34146031-2537AB2C-FEED-47D3-8E6D-A4C3E00D4927
P921
description
mammalian protein found in Mus musculus
@en
protein
@id
proteinë
@sq
proteïne in Interleukin 12b
@nl
protèin
@ace
بروتين في فأر المنازل
@ar
name
Interleukin 12b
@en
Interleukin 12b
@nl
type
label
Interleukin 12b
@en
Interleukin 12b
@nl
altLabel
CLMF p40
@en
IL-12 p40 subunit
@en
IL-12 subunit p40
@en
IL-23 subunit p40
@en
Il12b
@en
cytotoxic lymphocyte maturation factor 40 kDa subunit
@en
interleukin-12 p40 subunit
@en
interleukin-12 subunit beta
@en
prefLabel
Interleukin 12b
@en
Interleukin 12b
@nl
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NP_001290173