Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.
about
Bridge helix bending promotes RNA polymerase II backtracking through a critical and conserved threonine residueTranscription inhibition by the depsipeptide antibiotic salinamide AA genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelityActive Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In VivoDivergent contributions of conserved active site residues to transcription by eukaryotic RNA polymerases I and IIMillisecond dynamics of RNA polymerase II translocation at atomic resolutionTrigger loop folding determines transcription rate of Escherichia coli's RNA polymeraseA critical residue selectively recruits nucleotides for t7 RNA polymerase transcription fidelity control.Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.A two-state model for the dynamics of the pyrophosphate ion release in bacterial RNA polymerase.Crystal Structure of a Transcribing RNA Polymerase II Complex Reveals a Complete Transcription Bubble.The RNA polymerase bridge helix YFI motif in catalysis, fidelity and translocation.RNA polymerase stalls in a post-translocated register and can hyper-translocate.Energetic and structural details of the trigger-loop closing transition in RNA polymerase II.Direct assessment of transcription fidelity by high-resolution RNA sequencing.Computational simulation strategies for analysis of multisubunit RNA polymerases.Basic mechanisms of RNA polymerase II activity and alteration of gene expression in Saccharomyces cerevisiae.Molecular basis of transcriptional fidelity and DNA lesion-induced transcriptional mutagenesis.RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.T7 RNA polymerase translocation is facilitated by a helix opening on the fingers domain that may also prevent backtracking.The RNA polymerase trigger loop functions in all three phases of the transcription cycle.C(α) torsion angles as a flexible criterion to extract secrets from a molecular dynamics simulation.Hinge action versus grip in translocation by RNA polymerase.Dynamics of bridge helix bending in RNA polymerase II.RNA-DNA and DNA-DNA base-pairing at the upstream edge of the transcription bubble regulate translocation of RNA polymerase and transcription rate.THEORETICAL INVESTIGATIONS ON ELUCIDATING FUNDAMENTAL MECHANISMS OF CATALYSIS AND DYNAMICS INVOLVED IN TRANSCRIPTION BY RNA POLYMERASE
P2860
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P2860
Molecular dynamics and mutational analysis of the catalytic and translocation cycle of RNA polymerase.
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Molecular dynamics and mutatio ...... cation cycle of RNA polymerase
@nl
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@ast
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en-gb
type
label
Molecular dynamics and mutatio ...... cation cycle of RNA polymerase
@nl
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@ast
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en-gb
prefLabel
Molecular dynamics and mutatio ...... cation cycle of RNA polymerase
@nl
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@ast
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en-gb
P2093
P2860
P3181
P356
P1433
P1476
Molecular dynamics and mutatio ...... ation cycle of RNA polymerase.
@en
P2093
Kristopher Opron
Maria L Kireeva
Mikhail Kashlev
Robert I Cukier
Steve A Seibold
Zachary F Burton
P2860
P2888
P3181
P356
10.1186/2046-1682-5-11
P407
P577
2012-06-07T00:00:00Z
P5875
P6179
1025015401