Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
about
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop.Structures of E. coli σS-transcription initiation complexes provide new insights into polymerase mechanism.Regulation of transcription elongation and termination.Lineage-specific variations in the trigger loop modulate RNA proofreading by bacterial RNA polymerases.Kinetics of nucleotide entry into RNA polymerase active site provides mechanism for efficiency and fidelity.A structure-based kinetic model of transcription.Hinge action versus grip in translocation by RNA polymerase.An excited state underlies gene regulation of a transcriptional riboswitch.Trigger loop dynamics can explain stimulation of intrinsic termination by bacterial RNA polymerase without terminator hairpin contact.RNA-DNA and DNA-DNA base-pairing at the upstream edge of the transcription bubble regulate translocation of RNA polymerase and transcription rate.Active site closure stabilizes the backtracked state of RNA polymerase
P2860
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P2860
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
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2014 nî lūn-bûn
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2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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name
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
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Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
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type
label
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
@ast
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
@en
prefLabel
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
@ast
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
@en
P2860
P356
P1476
Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase
@en
P2093
Yara X Mejia
P2860
P304
P356
10.1073/PNAS.1421067112
P407
P577
2014-12-31T00:00:00Z