Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity
about
Human exonuclease 1 functionally complements its yeast homologues in DNA recombination, RNA primer removal, and mutation avoidanceThe RAD2 domain of human exonuclease 1 exhibits 5' to 3' exonuclease and flap structure-specific endonuclease activitiesMolecular interactions of human Exo1 with DNAArginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determinationStructural determinants for substrate binding and catalysis by the structure-specific endonuclease XPGRole of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damageSpartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage responsePoly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translationCrystal structure of a repair enzyme of oxidatively damaged DNA, MutM (Fpg), from an extreme thermophile, Thermus thermophilus HB8Managing DNA polymerases: coordinating DNA replication, DNA repair, and DNA recombinationOkazaki fragment maturation: nucleases take centre stageComparative genomics and molecular dynamics of DNA repeats in eukaryotesStructure and proposed activity of a member of the VapBC family of toxin-antitoxin systems. VapBC-5 from Mycobacterium tuberculosisThe 3'-flap pocket of human flap endonuclease 1 is critical for substrate binding and catalysisDNA replication in the archaeaDifferential interaction kinetics of a bipolar structure-specific endonuclease with DNA flaps revealed by single-molecule imagingStructure and function of a cap-independent translation element that functions in either the 3' or the 5' untranslated regionThe crystal structure of exonuclease RecJ bound to Mn2+ ion suggests how its characteristic motifs are involved in exonuclease activityMolecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshiiStructural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the -clampDistant structural homology leads to the functional characterization of an archaeal PIN domain as an exonucleaseCrystal structure of bacteriophage T4 5' nuclease in complex with a branched DNA reveals how flap endonuclease-1 family nucleases bind their substratesPCNA directs type 2 RNase H activity on DNA replication and repair substratesStructure of flap endonuclease 1 from the hyperthermophilic archaeonDesulfurococcus amylolyticusCrystal structure of a KSHV-SOX-DNA complex: insights into the molecular mechanisms underlying DNase activity and host shutoffHuman Flap Endonuclease Structures, DNA Double-Base Flipping, and a Unified Understanding of the FEN1 SuperfamilyStructures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease FamilyThe structure of Escherichia coli ExoIX--implications for DNA binding and catalysis in flap endonucleasesSaccharomyces cerevisiae RNase H(35) functions in RNA primer removal during lagging-strand DNA synthesis, most efficiently in cooperation with Rad27 nucleaseStimulation of 3'-->5' exonuclease and 3'-phosphodiesterase activities of yeast apn2 by proliferating cell nuclear antigen.Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate.Dna2p helicase/nuclease is a tracking protein, like FEN1, for flap cleavage during Okazaki fragment maturation.Proliferating cell nuclear antigen is protected from degradation by forming a complex with MutT Homolog2Phosphorylation of human Fen1 by cyclin-dependent kinase modulates its role in replication fork regulationThe active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif.Poly(A)-binding proteins regulate both mRNA deadenylation and decapping in yeast cytoplasmic extracts.A cis-acting element known to block 3' mRNA degradation enhances expression of polyA-minus mRNA in wild-type yeast cells and phenocopies a ski mutantMechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1The protein components and mechanism of eukaryotic Okazaki fragment maturation.Molecular interactions of Escherichia coli ExoIX and identification of its associated 3'-5' exonuclease activity.
P2860
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P2860
Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity
description
1998 nî lūn-bûn
@nan
1998 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@ast
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en-gb
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
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type
label
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@ast
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en-gb
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@nl
prefLabel
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@ast
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en-gb
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
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P2093
P921
P3181
P1433
P1476
Structure of the DNA repair an ...... PCNA binding to FEN-1 activity
@en
P2093
P304
P3181
P356
10.1016/S0092-8674(00)81789-4
P407
P577
1998-10-01T00:00:00Z