PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
about
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formationRegulation of the ubiquitin-conjugating enzyme hHR6A by CDK-mediated phosphorylationInsights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding proteinChoice of Plk1 docking partners during mitosis and cytokinesis is controlled by the activation state of Cdk1Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interferenceKIF14 and citron kinase act together to promote efficient cytokinesisHuman mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphaseMarking and measuring single microtubules by PRC1 and kinesin-4Spastin couples microtubule severing to membrane traffic in completion of cytokinesis and secretionLoss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescencePhosphorylation of mitotic kinesin-like protein 2 by polo-like kinase 1 is required for cytokinesisPlk1 negatively regulates PRC1 to prevent premature midzone formation before cytokinesis.Phosphorylation controls CLIMP-63-mediated anchoring of the endoplasmic reticulum to microtubulesThe pre-mRNA-splicing factor SF3a66 functions as a microtubule-binding and -bundling proteinRecruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cellsSpatiotemporal control of spindle midzone formation by PRC1 in human cellsBRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation siteAblation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does notCell cycle-dependent translocation of PRC1 on the spindle by Kif4 is essential for midzone formation and cytokinesis.Role of the midbody matrix in cytokinesis: RNAi and genetic rescue analysis of the mammalian motor protein CHO1.Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formationNPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcriptionThe 3Ms of central spindle assembly: microtubules, motors and MAPsMultistep regulation of DNA replication by Cdk phosphorylation of HsCdc6Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesisPRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzoneImmunobiology of hepatocarcinogenesis: Ways to go or almost there?Katanin p60 contributes to microtubule instability around the midbody and facilitates cytokinesis in rat cellsAugmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscissionCYK4 promotes antiparallel microtubule bundling by optimizing MKLP1 neck conformationKinetochore components are required for central spindle assembly.MAP65 coordinate microtubule growth during bundle formation.Dynamic proteomics of human protein level and localization across the cell cycleProtein dynamics in individual human cells: experiment and theoryCdc14-regulated midzone assembly controls anaphase BThe molecular function of Ase1p: evidence for a MAP-dependent midzone-specific spindle matrix. Microtubule-associated proteinsFission yeast Scp3 potentially maintains microtubule orientation through bundlingDraft De Novo Transcriptome of the Rat Kangaroo Potorous tridactylus as a Tool for Cell BiologyRole of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly.Modeling epigenetic regulation of PRC1 protein accumulation in the cell cycle.
P2860
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PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@ast
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en-gb
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@nl
type
label
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@ast
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en-gb
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@nl
prefLabel
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@ast
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en-gb
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@nl
P2093
P3181
P1433
P1476
PRC1: a human mitotic spindle-associated CDK substrate protein required for cytokinesis
@en
P2093
R Fukunaga
P304
P3181
P356
10.1016/S1097-2765(00)80302-0
P407
P577
1998-12-01T00:00:00Z