Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase
about
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formationPhosphoregulation of MgcRacGAP in mitosis involves Aurora B and Cdk1 protein kinases and the PP2A phosphataseAurora B and 14-3-3 coordinately regulate clustering of centralspindlin during cytokinesisEct2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosisSpatiotemporal control of spindle midzone formation by PRC1 in human cellsAblation of PRC1 by small interfering RNA demonstrates that cytokinetic abscission requires a central spindle bundle in mammalian cells, whereas completion of furrowing does notThe 3Ms of central spindle assembly: microtubules, motors and MAPsCep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesisCentralspindlin: at the heart of cytokinesisAPC(CDH1) targets MgcRacGAP for destruction in the late M phaseKinesins to the core: The role of microtubule-based motor proteins in building the mitotic spindle midzoneDirect association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-CEpithelial junctions and Rho family GTPases: the zonular signalosome.Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.Regulation of cytokinesis by Rho GTPase flux.In vivo imaging reveals a role for Cdc42 in spindle positioning and planar orientation of cell divisions during vertebrate neural tube closure.Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signalingElevated expression of protein regulator of cytokinesis 1, involved in the growth of breast cancer cells.MgcRacGAP interacts with cingulin and paracingulin to regulate Rac1 activation and development of the tight junction barrier during epithelial junction assemblyRho GTPases as regulators of mitosis and cytokinesis in mammalian cells.Molecular control of animal cell cytokinesis.Cytokinesis microtubule organisers at a glance.Direct interaction between centralspindlin and PRC1 reinforces mechanical resilience of the central spindle.Understanding cytokinesis failure.Midbodies and phragmoplasts: analogous structures involved in cytokinesis.Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cellsCurrent knowledge of the large RhoGAP family of proteins.Cell cycle regulation of Rho signaling pathways.Controlling the switches: Rho GTPase regulation during animal cell mitosis.Regulation of cytokinesis during corticogenesis: focus on the midbody.Quantitative proteome analysis of pluripotent cells by iTRAQ mass tagging reveals post-transcriptional regulation of proteins required for ES cell self-renewal.Cell type-specific regulation of RhoA activity during cytokinesis.Cell division: the need for speed.Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.Phosphorylation of NtMAP65-1 by a MAP kinase down-regulates its activity of microtubule bundling and stimulates progression of cytokinesis of tobacco cells.Central spindle robustness by PRC1-centralspindlin interaction.Mechanism of cell-intrinsic adaptation to Adams-Oliver Syndrome gene DOCK6 disruption highlights ubiquitin-like modifier ISG15 as a regulator of RHO GTPases.
P2860
Q21092734-A74FE9A0-94E7-4C6E-A976-B312AF6EA236Q24306750-7DC31872-8FFE-4372-AB67-954362E393F0Q24310798-83030851-7B59-4CD9-834B-559496081549Q24337741-15801965-5FC3-4730-ACF3-9D37055E6E97Q24546385-65AF2056-77FC-4A29-B929-7677A76E7EDFQ24556579-9E21917D-4D0E-46D8-B6C2-975D7416C0F2Q24645077-CF5495F1-D16F-4A76-B1B8-BBD518740536Q24670163-B83388D8-958F-46F3-8690-16EA8624823FQ27014502-79099C1B-9A42-4CAA-BDDC-3BC6E70D5150Q27321457-6BA23AE5-058C-4263-B114-9A8B44EB49C1Q28271618-D47AE86D-2177-4C82-B49E-01F4AD3C2A20Q28277516-1E57E2EE-E5B8-4BD1-A603-D38C1B10C03AQ30009261-66EA5ACE-81F7-4BDF-97FC-0CA3CA738AB8Q30414432-1253D577-5D29-4C7A-9488-81644E8A4357Q30439337-8A667E3D-3FCD-4294-81E3-650562C8B7FEQ30488562-1E35BFBC-5B79-4C84-BD0F-038B812CC482Q30650928-558E3659-08EB-44C4-AF2A-74217FC93171Q30856513-87126A73-1A76-4419-8F77-38F146B10806Q33269602-25FE8713-F2D0-4BBE-A8A3-F2B13B420074Q33811939-1FC57D91-37C8-412C-BF7E-2AB839A5FF60Q34160731-C656C0F6-C34C-4561-8B0D-9E97189FB470Q34272397-0CA0DFB4-44EF-49A5-B024-BBF508D2E03AQ34300588-BB44F2BE-653B-4E6F-997B-88EA3D5FEB36Q34481329-498FCC15-B0A8-42E0-9EA3-2772F8F787EBQ34717820-70D3DCC0-3D5E-48CE-8F67-75AFF0942A4CQ36189898-A9093666-7D68-40F8-B313-7E1850ED328FQ36643144-6CB7DAD4-DA8E-4466-BF10-6C8AC726C1F1Q36707513-3C2034FC-850F-46E5-B0B6-676F2E3D1352Q38028782-135072D1-2317-433B-9A3E-79E19FB37AE8Q38257062-885DCCCC-33C9-489C-88B9-A58713FD07C0Q39298424-581503F3-7943-45AF-BB50-ABF5656057F9Q39698217-BA87B337-8090-4A72-AD7F-ED791F7031ACQ40525937-E14AD867-1513-45BD-A681-710E6287A3ACQ41930709-81CFE742-BED1-4B1D-9741-E0B5E45C4C50Q41973279-61F5E943-1C0B-45C8-8BF2-518B9EB45687Q42083866-73E12CDB-0CDF-4937-9503-10BD969A2496Q42910324-39B53408-BC13-4DCB-986F-11667E1FC5F5Q51100814-1CADD5C8-F1FE-4F4A-AB67-B3AC0D07C62A
P2860
Human mitotic spindle-associated protein PRC1 inhibits MgcRacGAP activity toward Cdc42 during the metaphase
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@ast
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en-gb
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@nl
type
label
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@ast
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en-gb
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@nl
prefLabel
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@ast
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en-gb
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@nl
P2093
P2860
P356
P1476
Human mitotic spindle-associat ...... ard Cdc42 during the metaphase
@en
P2093
Hirofumi Tanaka
Kiyoko Fukami
Yasuhiro Irino
P2860
P304
P356
10.1074/JBC.M313257200
P407
P577
2004-04-16T00:00:00Z