Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein
about
Regulation of X11L-dependent amyloid precursor protein metabolism by XB51, a novel X11L-binding proteinDifferential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolismThe novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport.XB51 isoforms mediate Alzheimer's beta-amyloid peptide production by X11L (X11-like protein)-dependent and -independent mechanismsAutoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandemNovel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid beta-protein precursor metabolismDysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosisNuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cellsAutoinhibition of Mint1 adaptor protein regulates amyloid precursor protein binding and processingModulation of amyloid precursor protein metabolism by X11alpha /Mint-1. A deletion analysis of protein-protein interaction domains.The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocationThe neuronal adaptor protein X11alpha interacts with the copper chaperone for SOD1 and regulates SOD1 activityPDZ domain-dependent suppression of NF-kappaB/p65-induced Abeta42 production by a neuron-specific X11-like proteinSynergistic effects of Munc18a and X11 proteins on amyloid precursor protein metabolismIdentification of hepatopoietin dimerization, its interacting regions and alternative splicing of its transcriptionCoordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivationInteraction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascadeInteraction of Mint2 with TrkA is involved in regulation of nerve growth factor-induced neurite outgrowthAccidental interaction between PDZ domains and diclofenac revealed by NMR-assisted virtual screening.Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.Loss of c-Jun N-terminal kinase-interacting protein-1 does not affect axonal transport of the amyloid precursor protein or Aβ production.A new functional screening system for identification of regulators for the generation of amyloid beta-protein.Structural insight into GRIP1-PDZ6 in Alzheimer's disease: study from protein expression data to molecular dynamics simulations.Functions of WW domains in the nucleus.Role of X11 and ubiquilin as in vivo regulators of the amyloid precursor protein in DrosophilaThe cytoplasmic adaptor protein X11alpha and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement.Neuron-specific phosphorylation of Alzheimer's beta-amyloid precursor protein by cyclin-dependent kinase 5.Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like.The functions of the amyloid precursor protein gene.Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ productionProtein aggregates and dementia: is there a common toxicity?Cytoplasmic fragment of Alcadein α generated by regulated intramembrane proteolysis enhances amyloid β-protein precursor (APP) transport into the late secretory pathway and facilitates APP cleavage.Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.The fast and slow ups and downs of HCN channel regulation.Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue.Presenilin function and gamma-secretase activity.Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's diseaseTrafficking of Alzheimer's disease-related membrane proteins and its participation in disease pathogenesis.The role of presenilin and its interacting proteins in the biogenesis of Alzheimer's beta amyloidSorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.
P2860
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P2860
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Interaction of a neuron-specif ...... er's amyloid precursor protein
@ast
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en-gb
Interaction of a neuron-specif ...... er's amyloid precursor protein
@nl
type
label
Interaction of a neuron-specif ...... er's amyloid precursor protein
@ast
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en-gb
Interaction of a neuron-specif ...... er's amyloid precursor protein
@nl
prefLabel
Interaction of a neuron-specif ...... er's amyloid precursor protein
@ast
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en-gb
Interaction of a neuron-specif ...... er's amyloid precursor protein
@nl
P2093
P921
P356
P1476
Interaction of a neuron-specif ...... er's amyloid precursor protein
@en
P2093
S Sakiyama
P304
P356
10.1074/JBC.274.4.2243
P407
P577
1999-01-22T00:00:00Z