The fast and slow ups and downs of HCN channel regulation.
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Searching for new targets for treatment of pediatric epilepsyIdentification of Small-Molecule Inhibitors of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels.Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.TRIP8b-independent trafficking and plasticity of adult cortical presynaptic HCN1 channels.Regulation of axonal HCN1 trafficking in perforant path involves expression of specific TRIP8b isoforms.HCN channels in behavior and neurological disease: too hyper or not active enough?A di-arginine ER retention signal regulates trafficking of HCN1 channels from the early secretory pathway to the plasma membrane.Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent mannerThe Role of HCN Channels on Membrane Excitability in the Nervous SystemAssociation of polymorphisms in HCN4 with mood disorders and obsessive compulsive disorder.Filamin A promotes dynamin-dependent internalization of hyperpolarization-activated cyclic nucleotide-gated type 1 (HCN1) channels and restricts Ih in hippocampal neurons.Towards an integrated view of HCN channel role in epilepsy.HCN Channels Modulators: The Need for Selectivity.Differential regulation of HCN channel isoform expression in thalamic neurons of epileptic and non-epileptic rat strains.Up-regulation of hyperpolarization-activated cyclic nucleotide-gated channel 3 (HCN3) by specific interaction with K+ channel tetramerization domain-containing protein 3 (KCTD3).Hyperpolarization-activated cation current Ih of dentate gyrus granule cells is upregulated in human and rat temporal lobe epilepsy.Differences in the expression pattern of HCN isoforms among mammalian tissues: sources and implications.Loss of HCN2 leads to delayed gastrointestinal motility and reduced energy intake in mice.
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The fast and slow ups and downs of HCN channel regulation.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
The fast and slow ups and downs of HCN channel regulation.
@ast
The fast and slow ups and downs of HCN channel regulation.
@en
type
label
The fast and slow ups and downs of HCN channel regulation.
@ast
The fast and slow ups and downs of HCN channel regulation.
@en
prefLabel
The fast and slow ups and downs of HCN channel regulation.
@ast
The fast and slow ups and downs of HCN channel regulation.
@en
P2860
P356
P1433
P1476
The fast and slow ups and downs of HCN channel regulation
@en
P2093
Chad M Estep
Dane M Chetkovich
P2860
P304
P356
10.4161/CHAN.4.3.11630
P577
2010-05-01T00:00:00Z