Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet
about
Preparing synthetic biology for the worldA semi-synthetic organism with an expanded genetic alphabetGeneration of high-affinity DNA aptamers using an expanded genetic alphabetNon-Standard Genetic Codes Define New Concepts for Protein EngineeringLibrary construction for next-generation sequencing: overviews and challenges.Structural Insights into DNA Replication without Hydrogen BondsA Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase PairSystematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabetSequence-controlled polymers.Synthetic biology: New letters for life's alphabet.DNA ligase-mediated translation of DNA into densely functionalized nucleic acid polymersA semisynthetic organism engineered for the stable expansion of the genetic alphabet.Synthesis of 2,6-disubstituted pyridin-3-yl C-2'-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides.Evolution of functional six-nucleotide DNA.Biological phosphorylation of an Unnatural Base Pair (UBP) using a Drosophila melanogaster deoxynucleoside kinase (DmdNK) mutant.Identification of DNA lesions using a third base pair for amplification and nanopore sequencing.The expanded genetic alphabet.Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps.Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases.Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair.DNA interstrand cross-linking upon irradiation of aryl halide C-nucleotides.Site-specifically arraying small molecules or proteins on DNA using an expanded genetic alphabetSynthetic chromosomes.Overcoming Challenges in Engineering the Genetic CodeIn Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism.Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications.Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells.Ribonucleosides for an artificially expanded genetic information system.Cycloadditions for Studying Nucleic Acids.Chemical Stabilization of Unnatural Nucleotide Triphosphates for the in Vivo Expansion of the Genetic Alphabet.Site-specific labeling of RNA by combining genetic alphabet expansion transcription and copper-free click chemistry.Homochiral oligomers with highly flexible backbones form stable H-bonded duplexes.Genetics just got SEXY: Sequences encoding XYThe genetic code. Rewritten, revised, repurposed.Polymerase recognition of a Watson-Crick-like metal-mediated base pair: purine-2,6-dicarboxylate⋅copper(II)⋅ pyridine.Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology.Evolving Aptamers with Unnatural Base Pairs.Synthetic evolutionary origin of a proofreading reverse transcriptase.Reply to Hettinger: Hydrophobic unnatural base pairs and the expansion of the genetic alphabet.Helix instability and self-pairing prevent unnatural base pairs from expanding the genetic alphabet.
P2860
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P2860
Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet
description
2012 nî lūn-bûn
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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2012年の論文
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2012年論文
@yue
2012年論文
@zh-hant
2012年論文
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2012年論文
@zh-mo
2012年論文
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2012年论文
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name
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@ast
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en-gb
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@nl
type
label
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@ast
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en-gb
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@nl
prefLabel
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@ast
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en-gb
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@nl
P2093
P2860
P356
P1476
Efficient and sequence-indepen ...... al six-letter genetic alphabet
@en
P2093
Denis A Malyshev
Floyd E Romesberg
Henry T Quach
Kirandeep Dhami
Phillip Ordoukhanian
P2860
P304
12005-12010
P356
10.1073/PNAS.1205176109
P407
P577
2012-07-06T00:00:00Z