KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry - Wikidata - awgldk - TriplyDB

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

http://www.wikidata.org/entity/Q27679464

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Preparing synthetic biology for the world A semi-synthetic organism with an expanded genetic alphabet Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet Structural Insights into DNA Replication without Hydrogen Bonds Structures of KOD and 9°N DNA polymerases complexed with primer template duplex Structure and function of an RNA-reading thermostable DNA polymerase A Crystal Structure of a Functional RNA Molecule Containing an Artificial Nucleobase Pair RB69 DNA polymerase structure, kinetics, and fidelity.Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet A semisynthetic organism engineered for the stable expansion of the genetic alphabet.Synthesis of 2,6-disubstituted pyridin-3-yl C-2'-deoxyribonucleosides through chemoselective transformations of bromo-chloropyridine C-nucleosides.A conservative isoleucine to leucine mutation causes major rearrangements and cold sensitivity in KlenTaq1 DNA polymerase Evolution of functional six-nucleotide DNA.The Toolbox for Modified Aptamers.Structural basis for a six nucleotide genetic alphabet.The expanded genetic alphabet.Expanding the scope of replicable unnatural DNA: stepwise optimization of a predominantly hydrophobic base pair.DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotides Synthetic biology approaches to biological containment: pre-emptively tackling potential risks.In Vivo Structure-Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism.Natural-like replication of an unnatural base pair for the expansion of the genetic alphabet and biotechnology applications.How do hydrophobic nucleobases differ from natural DNA nucleobases? Comparison of structural features and duplex properties from QM calculations and MD simulations.Synthetic Biology Parts for the Storage of Increased Genetic Information in Cells.Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides.The expanding world of DNA and RNA.Cycloadditions for Studying Nucleic Acids.Chemical Stabilization of Unnatural Nucleotide Triphosphates for the in Vivo Expansion of the Genetic Alphabet.Influence of 5-N-carboxamide modifications on the thermodynamic stability of oligonucleotides.Direct sensing of 5-methylcytosine by polymerase chain reaction.Processive Incorporation of Deoxynucleoside Triphosphate Analogs by Single-Molecule DNA Polymerase I (Klenow Fragment) Nanocircuits.Exploring the Chemistry of Genetic Information Storage and Propagation through Polymerase Engineering.Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2'-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase η.Synthetic polymers and their potential as genetic materials.Recent progress in dissecting molecular recognition by DNA polymerases with non-native substrates.Expansion of the Genetic Alphabet: A Chemist's Approach to Synthetic Biology.Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet.Structural basis for the selective incorporation of an artificial nucleotide opposite a DNA adduct by a DNA polymerase.Can a Six-Letter Alphabet Increase the Likelihood of Photochemical Assault to the Genetic Code?Structure and Biophysics for a Six Letter DNA Alphabet that Includes Imidazo[1,2-a]-1,3,5-triazine-2(8H)-4(3H)-dione (X) and 2,4-Diaminopyrimidine (K).Structural Basis for Expansion of the Genetic Alphabet with an Artificial Nucleobase Pair.

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KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

http://www.wikidata.org/entity/Q27679464

description

2012 nî lūn-bûn

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2012 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի հուլիսին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@ast

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@en

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

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type

label

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@ast

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@en

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

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prefLabel

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@ast

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@en

KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

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Nature Chemical Biology

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KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry

@en

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Andreas Marx

http://www.w3.org/2001/XMLSchema#string

Denis A Malyshev

http://www.w3.org/2001/XMLSchema#string

Floyd E Romesberg

http://www.w3.org/2001/XMLSchema#string

Karin Betz

http://www.w3.org/2001/XMLSchema#string

Phillip Ordoukhanian

http://www.w3.org/2001/XMLSchema#string

Tammy J Dwyer

http://www.w3.org/2001/XMLSchema#string

Thomas Lavergne

http://www.w3.org/2001/XMLSchema#string

P2860

Nanomaterials based on DNA

Efforts toward Expansion of the Genetic Alphabet: Structure and Replication of Unnatural Base Pairs

Solution Structure, Mechanism of Replication, and Optimization of an Unnatural Base Pair

The structure of a high fidelity DNA polymerase bound to a mismatched nucleotide reveals an "ajar" intermediate conformation in the nucleotide selection mechanism.

Crystal structure of a bacteriophage T7 DNA replication complex at 2.2 A resolution

Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet

An unnatural hydrophobic base pair system: site-specific incorporation of nucleotide analogs into DNA and RNA

Crystal structures of open and closed forms of binary and ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I: structural basis for nucleotide incorporation.

Discovery, characterization, and optimization of an unnatural base pair for expansion of the genetic alphabet.

Optimization of an unnatural base pair toward natural-like replication

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612-4

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scholarly article

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3693208

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10.1038/NCHEMBIO.966

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7

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8

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2012-07-01T00:00:00Z

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225097861

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1018428867

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22660438

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3690913

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