Coreceptors--Implications for HIV Pathogenesis and Therapy
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Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT miceDefinition of the stage of host cell genetic restriction of replication of human immunodeficiency virus type 1 in monocytes and monocyte-derived macrophages by using twins.Bioinformatic analysis of HIV-1 entry and pathogenesis.Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibodyGenealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progressionEffects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy.HIV infection of megakaryocytic cell lines.Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kineticsNeutralizing antibodies in sera from macaques infected with chimeric simian-human immunodeficiency virus containing the envelope glycoproteins of either a laboratory-adapted variant or a primary isolate of human immunodeficiency virus type 1.Naïve and memory CD4 T cells differ in their susceptibilities to human immunodeficiency virus type 1 infection following CD28 costimulation: implicatip6s for transmission and pathogenesis.Oligomeric modeling and electrostatic analysis of the gp120 envelope glycoprotein of human immunodeficiency virus.A polymorphism in the regulatory region of the CC-chemokine receptor 5 gene influences perinatal transmission of human immunodeficiency virus type 1 to African-American infantsComparative analysis of protein interaction networks reveals that conserved pathways are susceptible to HIV-1 interception.Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry.Impact of alcohol on the ability of Kupffer cells to produce chemokines and its role in alcoholic liver disease.Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5.An expanded model of HIV cell entry phenotype based on multi-parameter single-cell data.Effects of CYP3A4 inducers with and without CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.Mechanisms of Host Resistance Against HIV Infection and Progression to AIDS.Separate cellular localizations of human T-lymphotropic virus 1 (HTLV-1) Env and glucose transporter type 1 (GLUT1) are required for HTLV-1 Env-mediated fusion and infection.HIV-1 neuropathogenesis: glial mechanisms revealed through substance abuseStabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimeticDiscovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development.Forward Look: Tenth Anniversary of the Human Genome Sequence and 21 Century Postgenomics Global Health - A Close Up on Africa and Women's Health.Transcription factor GATA-1 potently represses the expression of the HIV-1 coreceptor CCR5 in human T cells and dendritic cells.Morphine and gp120 toxic interactions in striatal neurons are dependent on HIV-1 strain.Cell surface expression of CCR5 and other host factors influence the inhibition of HIV-1 infection of human lymphocytes by CCR5 ligands.Use of a small molecule CCR5 inhibitor in macaques to treat simian immunodeficiency virus infection or prevent simian-human immunodeficiency virus infection.CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro.Engineered lentiviral vectors pseudotyped with a CD4 receptor and a fusogenic protein can target cells expressing HIV-1 envelope proteins.Down-regulation of cell surface CXCR4 by HIV-1Atomic force microscopy investigation of human immunodeficiency virus (HIV) and HIV-infected lymphocytes.The differential sensitivity of human and rhesus macaque CCR5 to small-molecule inhibitors of human immunodeficiency virus type 1 entry is explained by a single amino acid difference and suggests a mechanism of action for these inhibitorsBasophils: what they 'can do' versus what they 'actually do'.Human immunodeficiency virus type 1 V1-to-V5 envelope variants from the chronic phase of infection use CCR5 and fuse more efficiently than those from early after infection.Identification of novel host-oriented targets for Human Immunodeficiency Virus type 1 using Random Homozygous Gene Perturbation.C-C chemokine receptor type five (CCR5): An emerging target for the control of HIV infection.Recent patents regarding the discovery of small molecule CXCR4 antagonists.Human endothelial cells enhance human immunodeficiency virus type 1 replication in CD4+ T cells in a Nef-dependent manner in vitro and in vivo
P2860
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P2860
Coreceptors--Implications for HIV Pathogenesis and Therapy
description
1997 nî lūn-bûn
@nan
1997 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Coreceptors--Implications for HIV Pathogenesis and Therapy
@ast
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en-gb
Coreceptors: implications for HIV pathogenesis and therapy.
@nl
type
label
Coreceptors--Implications for HIV Pathogenesis and Therapy
@ast
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en-gb
Coreceptors: implications for HIV pathogenesis and therapy.
@nl
altLabel
Coreceptors: implications for HIV pathogenesis and therapy.
@ast
Coreceptors: implications for HIV pathogenesis and therapy.
@en
prefLabel
Coreceptors--Implications for HIV Pathogenesis and Therapy
@ast
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en-gb
Coreceptors: implications for HIV pathogenesis and therapy.
@nl
P1433
P1476
Coreceptors--Implications for HIV Pathogenesis and Therapy
@en
Coreceptors: implications for HIV pathogenesis and therapy.
@en
P2093
P356
10.1126/SCIENCE.276.5309.51
P407
P577
1997-04-01T00:00:00Z
1997-04-04T00:00:00Z