Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
about
Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpointp31comet blocks Mad2 activation through structural mimicryShugoshin is a Mad1/Cdc20-like interactor of Mad2Determinants of conformational dimerization of Mad2 and its inhibition by p31cometCentromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome lossMad2 binding to Mad1 and Cdc20, rather than oligomerization, is required for the spindle checkpoint.Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulationMicrotubule-dependent changes in assembly of microtubule motor proteins and mitotic spindle checkpoint proteins at PtK1 kinetochoresConformation-specific binding of p31(comet) antagonizes the function of Mad2 in the spindle checkpointStructural analysis of Bub3 interactions in the mitotic spindle checkpointStructural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template modelThe multifaceted roles of the HORMA domain in cellular signalingThe current view for the silencing of the spindle assembly checkpointInsights into Mad2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric Mad2 DimerA HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagyStructure of the mitotic checkpoint complexStructure of the Atg101-Atg13 complex reveals essential roles of Atg101 in autophagy initiationThe APC/C subunit Mnd2/Apc15 promotes Cdc20 autoubiquitination and spindle assembly checkpoint inactivation.Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteinsIn-silico modeling of the mitotic spindle assembly checkpointThe transcription factor TFII-I promotes DNA translesion synthesis and genomic stabilityConnecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint.Structural gymnastics of multifunctional metamorphic proteins.Taxol-stabilized microtubules can position the cytokinetic furrow in mammalian cells.Recruitment of Cdc20 to the kinetochore requires BubR1 but not Mad2 in Drosophila melanogaster.The influence of catalysis on mad2 activation dynamics.Molecular dynamics simulation on the conformational transition of the mad2 protein from the open to the closed state.Cdc20: a potential novel therapeutic target for cancer treatmentRole of the Na ⁺/K ⁺/2Cl⁻ cotransporter NKCC1 in cell cycle progression in human esophageal squamous cell carcinoma.The spindle checkpoint, aneuploidy, and cancer.Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer.The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium.Proteins that switch foldsWT1 interacts with MAD2 and regulates mitotic checkpoint functionThe dynamics of signal amplification by macromolecular assemblies for the control of chromosome segregationPhosphorylation of the spindle checkpoint protein Mad2 regulates its conformational transition.Mad2 inhibits the mitotic kinesin MKlp2.Chromosome-wide regulation of meiotic crossover formation in Caenorhabditis elegans requires properly assembled chromosome axes.Mad2 phosphorylation regulates its association with Mad1 and the APC/C.
P2860
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P2860
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
description
2000 nî lūn-bûn
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2000 թուականի Մարտին հրատարակուած գիտական յօդուած
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2000 թվականի մարտին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
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2000年论文
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name
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@ast
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en-gb
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@nl
type
label
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@ast
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en-gb
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@nl
prefLabel
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@ast
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en-gb
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@nl
P2093
P921
P3181
P356
P1476
Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20
@en
P2093
M Coldiron
M W Kirschner
P3181
P356
10.1038/73338
P407
P577
2000-03-01T00:00:00Z