Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes
about
Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in miceNew role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditureNeurohumoral stimulation in type-2-diabetes as an emerging disease conceptProtein tyrosine phosphatase 1B deficiency potentiates PERK/eIF2α signaling in brown adipocytesPositive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signalingInsulin-like growth factor 1 receptor signaling regulates skin development and inhibits skin keratinocyte differentiationInterleukin-6 is a positive regulator of tumor necrosis factor alpha-induced adipose-related protein in 3T3-L1 adipocytesTyk2 and Stat3 regulate brown adipose tissue differentiation and obesityA dominant-negative p38 MAPK mutant and novel selective inhibitors of p38 MAPK reduce insulin-stimulated glucose uptake in 3T3-L1 adipocytes without affecting GLUT4 translocation.Using biological performance similarity to inform disaccharide library design.Regulation of brown fat adipogenesis by protein tyrosine phosphatase 1BCellular bioenergetics as a target for obesity therapy.Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in miceCharacterization of the Met326Ile variant of phosphatidylinositol 3-kinase p85alphaUp-regulation of the Sirtuin 1 (Sirt1) and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) genes in white adipose tissue of Id1 protein-deficient mice: implications in the protection against diet and age-induced glucose intoleraSubcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytesReduced UCP-1 content in in vitro differentiated beige/brite adipocytes derived from preadipocytes of human subcutaneous white adipose tissues in obesity.Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis.Insulin/IGF-I regulation of necdin and brown adipocyte differentiation via CREB- and FoxO1-associated pathways.Lipoatrophic diabetes in Irs1(-/-)/Irs3(-/-) double knockout mice.The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance.Differential roles of insulin receptor substrates in brown adipocyte differentiation.Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1Novel roles for insulin receptor (IR) in adipocytes and skeletal muscle cells via new and unexpected substrates.Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1.Altered thermogenesis and impaired bone remodeling in Misty miceExpression and function of the insulin receptor substrate proteins in cancerA multifunctional protein, EWS, is essential for early brown fat lineage determination.Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat DietInvolvement of insulin receptor substrate 2 in mammary tumor metastasis.ApoA-IV improves insulin sensitivity and glucose uptake in mouse adipocytes via PI3K-Akt Signaling.Improved methodologies for the study of adipose biology: insights gained and opportunities ahead.Metabolic inflammation: connecting obesity and insulin resistance.Regulation of GLUT4 and Insulin-Dependent Glucose Flux.Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.Depot-specific adipocyte cell lines reveal differential drug-induced responses of white adipocytes--relevance for partial lipodystrophy.Differential roles of the insulin and insulin-like growth factor-I (IGF-I) receptors in response to insulin and IGF-I.Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.Differential roles of insulin receptor substrates in the anti-apoptotic function of insulin-like growth factor-1 and insulin.Atypical beta-adrenergic effects on insulin signaling and action in beta(3)-adrenoceptor-deficient brown adipocytes.
P2860
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P2860
Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes
description
2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
@zh-hant
2000年論文
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2000年論文
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2000年論文
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2000年论文
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name
Essential role of insulin rece ...... ose uptake in brown adipocytes
@ast
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en-gb
Essential role of insulin rece ...... ose uptake in brown adipocytes
@nl
type
label
Essential role of insulin rece ...... ose uptake in brown adipocytes
@ast
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en-gb
Essential role of insulin rece ...... ose uptake in brown adipocytes
@nl
prefLabel
Essential role of insulin rece ...... ose uptake in brown adipocytes
@ast
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en-gb
Essential role of insulin rece ...... ose uptake in brown adipocytes
@nl
P2093
P2860
P3181
P356
P1476
Essential role of insulin rece ...... ose uptake in brown adipocytes
@en
P2093
P2860
P304
P3181
P356
10.1074/JBC.M004046200
P407
P577
2000-08-18T00:00:00Z