about
P688
Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cellsGenetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of FhitFhit is a physiological target of the protein kinase SrcStructure-based analysis of catalysis and substrate definition in the HIT protein familyFhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolaseThe FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancersMAD analysis of FHIT, a putative human tumor suppressor from the HIT protein familyThe tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.
P921
Q24301436-7968F115-A8BF-4F69-90B0-3BA243732D9CQ24313542-80BDD455-2620-4EFA-9A93-22C565A410C9Q24315088-9C862702-24C7-4B7C-A67D-8510A45E570DQ24316188-B61620AB-0FDD-4C8E-A6AB-1C68EBB550DDQ24320228-D4DE54D1-2526-47EC-8567-4E8734E12D80Q24321912-0C4BF2DC-6442-4E58-856B-3AD80BB16686Q24323388-182FD50C-D93D-456F-A043-6EB531B64369Q36299944-86701915-6604-439F-91C3-71D9DF62E2A6Q37718255-5E0C0DF1-C839-478B-AC59-58AA12738529
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
proteïne in Fragile histidine triad
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Fragile histidine triad diadenosine triphosphatase
@en
type
label
Fragile histidine triad diadenosine triphosphatase
@en
altLabel
AP3A hydrolase
@en
AP3Aase
@en
FHIT
@en
Fragile histidine triad protein
@en
bis(5'-adenosyl)-triphosphatase
@en
diadenosine 5',5'''-P1,P3-triphosphate hydrolase
@en
dinucleosidetriphosphatase
@en
prefLabel
Fragile histidine triad diadenosine triphosphatase
@en
P637
P638
P680
P681
P682
P705
P352
P279
P31
P352
P637
NP_001159715
NP_001307828
NP_001307829
NP_001307830
NP_001341518
NP_001341519
P638
P680
P682
P702
P703
P705
ENSP00000342087
ENSP00000417480
ENSP00000417557
ENSP00000418582
ENSP00000418596