Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells
about
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cellsTargeting of Mutant p53 and the Cellular Redox Balance by APR-246 as a Strategy for Efficient Cancer TherapyA hybrid machine learning-based method for classifying the Cushing's Syndrome with comorbid adrenocortical lesions.Activation state-dependent interaction between Gαq subunits and the Fhit tumor suppressor.High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesisFhit, a tumor suppressor protein, induces autophagy via 14-3-3τ in non-small cell lung cancer cells.WWOX gene restoration prevents lung cancer growth in vitro and in vivoREGgamma modulates p53 activity by regulating its cellular localization.Hits, Fhits and Nits: beyond enzymatic function.Effect of eradication of Helicobacter pylori on expression levels of FHIT, IL-8 and P73 in gastric mucosa of first-degree relatives of gastric cancer patients.Signatures of human regulatory T cells: an encounter with old friends and new playersActivating enhancer-binding protein-2β nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection.Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells.The effect of adenovirus-mediated gene expression of FHIT in small cell lung cancer cells.Genetic alterations in urothelial bladder carcinoma: an updated review.The expression of FHIT, PCNA and EGFR in benign and malignant breast lesionsFragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea.Fhit tumor suppressor: guardian of the preneoplastic genome.Specifically targeted gene therapy for small-cell lung cancer.Increased sensitivity to cisplatin in non-small cell lung cancer cell lines after FHIT gene transfer.Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.Notch1 is required for Kras-induced lung adenocarcinoma and controls tumor cell survival via p53Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells.Computational Survey of FHIT, A Putative Human Tumor Suppressor, Truncates Structure.The antitumor activity of TRAIL and IL-24 with replicating oncolytic adenovirus in colorectal cancer.In silico study of fragile histidine triad interaction domains with MDM2 and p53.Synergistic effects of eukaryotic coexpression plasmid carrying LKB1 and FUS1 genes on lung cancer in vitro and in vivo.Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma.Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction.Fhit
P2860
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P2860
Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Synergistic tumor suppression ...... n-small cell lung cancer cells
@ast
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en-gb
Synergistic tumor suppression ...... n-small cell lung cancer cells
@nl
type
label
Synergistic tumor suppression ...... n-small cell lung cancer cells
@ast
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en-gb
Synergistic tumor suppression ...... n-small cell lung cancer cells
@nl
prefLabel
Synergistic tumor suppression ...... n-small cell lung cancer cells
@ast
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en-gb
Synergistic tumor suppression ...... n-small cell lung cancer cells
@nl
P2093
P1433
P1476
Synergistic tumor suppression ...... n-small cell lung cancer cells
@en
P2093
Bingliang Fang
Jack A Roth
Ji-Ichiro Sasaki
John D Minna
Masahiko Nishizaki
P304
P356
10.1158/0008-5472.CAN-04-0195
P407
P577
2004-08-15T00:00:00Z