Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase
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Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosisVanadium-induced nuclear factor of activated T cells activation through hydrogen peroxideP21-activated protein kinase (PAK2)-mediated c-Jun phosphorylation at 5 threonine sites promotes cell transformationS1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism.Mitogen-activated protein kinase activation in UV-induced signal transduction.Anti-cancer effects of JKA97 are associated with its induction of cell apoptosis via a Bax-dependent and p53-independent pathway.Involvement of ROS/ASMase/JNK signalling pathway in inhibiting UVA-induced apoptosis of HaCaT cells by polypeptide from Chlamys farreri.Role of ceramide in Ca2+-sensing receptor-induced apoptosis.Activation of the JAK/STAT pathway by ceramide in cultured human fibroblasts.Inhibitory mechanisms of tea polyphenols on the ultraviolet B-activated phosphatidylinositol 3-kinase-dependent pathway.Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester.Mitogen- and stress-activated protein kinase 1 mediates activation of Akt by ultraviolet B irradiation.Activation of p38 MAP kinase and ERK are required for ultraviolet-B induced c-fos gene expression in human keratinocytes.JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoylphorbol-13-acetate.The extracellular-signal-regulated protein kinases (Erks) are required for UV-induced AP-1 activation in JB6 cells.Translocation of protein kinase Cepsilon and protein kinase Cdelta to membrane is required for ultraviolet B-induced activation of mitogen-activated protein kinases and apoptosis.Activation of a p53-independent, sphingolipid-mediated cytolytic pathway in p53-negative mouse fibroblast cells treated with N-methyl-N-nitro-N-nitrosoguanidine.Inositol hexaphosphate inhibits ultraviolet B-induced signal transduction.Activation of JNK1, RSK2, and MSK1 is involved in serine 112 phosphorylation of Bad by ultraviolet B radiation.Lovastatin causes sensitization of HeLa cells to ionizing radiation-induced apoptosis by the abrogation of G2 blockage.Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells.EB1089 induces Skp2-dependent p27 accumulation, leading to cell growth inhibition and cell cycle G1 phase arrest in human hepatoma cells.Essential roles of PI-3K/Akt/IKKbeta/NFkappaB pathway in cyclin D1 induction by arsenite in JB6 Cl41 cells.Caenorhabditis elegans contains two distinct acid sphingomyelinases.Analysis of human breast adenocarcinoma MCF7 resistance to tumor necrosis factor-induced cell death. Lack of correlation between JNK activation and ceramide pathway.
P2860
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P2860
Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase
description
1997 nî lūn-bûn
@nan
1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@ast
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en-gb
type
label
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@ast
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en-gb
prefLabel
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@ast
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en-gb
P2093
P2860
P356
P1476
Direct evidence for an importa ...... ion of c-Jun N-terminal kinase
@en
P2093
P2860
P2880
P304
27753-27757
P356
10.1074/JBC.272.44.27753
P407
P50
P577
1997-10-31T00:00:00Z