Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
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Bile acids: regulation of apoptosis by ursodeoxycholic acidBile acids: regulation of synthesisBile acid signaling in metabolic disease and drug therapyMultiple cyclin kinase inhibitors promote bile acid-induced apoptosis and autophagy in primary hepatocytes via p53-CD95-dependent signalingHydrophobic bile salts trigger ceramide formation through endosomal acidificationPhosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cellsFarnesoid X receptor is essential for normal glucose homeostasisDeoxycholate, an endogenous cytotoxin/genotoxin, induces the autophagic stress-survival pathway: implications for colon carcinogenesis.Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse.Acidic sphingomyelinase controls hepatic stellate cell activation and in vivo liver fibrogenesisSorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells.INTRACELLULAR SIGNALING BY BILE ACIDS.Bile acid signaling in lipid metabolism: metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice.Decreasing mitochondrial fission prevents cholestatic liver injuryFusobacterium and Escherichia: models of colorectal cancer driven by microbiota and the utility of microbiota in colorectal cancer screening.Hydrophobic bile acid apoptosis is regulated by sphingosine-1-phosphate receptor 2 in rat hepatocytes and human hepatocellular carcinoma cells.Translational biomarkers of acetaminophen-induced acute liver injuryBile Acid Receptors and Liver Cancer.Vorinostat and sorafenib synergistically kill tumor cells via FLIP suppression and CD95 activation.Mitogen-activated protein kinase kinase 1/2 inhibitors and 17-allylamino-17-demethoxygeldanamycin synergize to kill human gastrointestinal tumor cells in vitro via suppression of c-FLIP-s levels and activation of CD95.Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules.Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.Vorinostat and sorafenib increase ER stress, autophagy and apoptosis via ceramide-dependent CD95 and PERK activationBile acids as regulatory molecules.c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver.Ceramide formation mediated by acid sphingomyelinase facilitates endosomal escape of caliciviruses.Vorinostat and sorafenib increase CD95 activation in gastrointestinal tumor cells through a Ca(2+)-de novo ceramide-PP2A-reactive oxygen species-dependent signaling pathway.Keratin impact on PKCδ- and ASMase-mediated regulation of hepatocyte lipid raft size - implication for FasR-associated apoptosis.Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice.Role of caspases in CD95-induced biphasic activation of acid sphingomyelinase.Role of bile acids in liver injury and regeneration following acetaminophen overdose.Regulation of autophagy by ceramide-CD95-PERK signaling.Bile acid flux through portal but not peripheral veins inhibits CYP7A1 expression without involvement of ileal FGF19 in rabbits.The constitutive androstane receptor and pregnane X receptor function coordinately to prevent bile acid-induced hepatotoxicity.Loss of cellular FLICE-inhibitory protein promotes acute cholestatic liver injury and inflammation from bile duct-ligation.Bile acids as global regulators of hepatic nutrient metabolismEndosomal Acidification and Activation of NADPH Oxidase Isoforms Are Upstream Events in Hyperosmolarity-induced Hepatocyte Apoptosis
P2860
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P2860
Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh
2003年學術文章
@zh-hant
name
Deoxycholic acid activates the ...... on in FAS receptor activation.
@en
Deoxycholic acid activates the ...... on in FAS receptor activation.
@nl
type
label
Deoxycholic acid activates the ...... on in FAS receptor activation.
@en
Deoxycholic acid activates the ...... on in FAS receptor activation.
@nl
prefLabel
Deoxycholic acid activates the ...... on in FAS receptor activation.
@en
Deoxycholic acid activates the ...... on in FAS receptor activation.
@nl
P2093
P2860
P50
P356
P1476
Deoxycholic acid activates the ...... on in FAS receptor activation.
@en
P2093
Elaine J Studer
Phillip B Hylemon
Seema Gupta
Shawn G Payne
P2860
P304
P356
10.1074/JBC.M310979200
P407
P577
2003-12-02T00:00:00Z