Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
about
Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activityRanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolismGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateN-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulumEndoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseA product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell deathParkin mono-ubiquitinates Bcl-2 and regulates autophagyParkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer modelAutoregulation of Parkin activity through its ubiquitin-like domainA ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of ParkinParkin accumulation in aggresomes due to proteasome impairmentParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stressParkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradationHuman HRD1 protects against ER stress-induced apoptosis through ER-associated degradationHerp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stressInvolvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell deathHow does parkin ligate ubiquitin to Parkinson's disease?Interferon-inducible ubiquitin E2, Ubc8, is a conjugating enzyme for protein ISGylationStructure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7)Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathyDorfin localizes to the ubiquitylated inclusions in Parkinson's disease, dementia with Lewy bodies, multiple system atrophy, and amyotrophic lateral sclerosisParkin counteracts symptoms in a Drosophila model of Parkinson's disease.Rheumatoid arthritis as a hyper-endoplasmic-reticulum-associated degradation diseaseParkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicityCHIP: A new modulator of human malignant disordersParkin Regulation and Neurodegenerative DisordersDrug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1Endoplasmic Reticulum Stress Interacts With Inflammation in Human DiseasesRBR E3 ubiquitin ligases: new structures, new insights, new questionsXenobiotic perturbation of ER stress and the unfolded protein responsePathologic and therapeutic implications for the cell biology of parkinThe delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiologyMetabolic syndrome: an important risk factor for Parkinson's diseasePhosphorylation of mitochondrial polyubiquitin by PINK1 promotes Parkin mitochondrial tetheringPINK1-mediated phosphorylation of Parkin boosts Parkin activity in DrosophilaCell-permeable parkin proteins suppress Parkinson disease-associated phenotypes in cultured cells and animalsParkin binds the Rpn10 subunit of 26S proteasomes through its ubiquitin-like domainA molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
P2860
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P2860
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
description
2000 nî lūn-bûn
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2000 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2000 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2000年の論文
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2000年学术文章
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2000年学术文章
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2000年学术文章
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name
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@ast
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en-gb
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@nl
type
label
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@ast
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en-gb
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@nl
prefLabel
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@ast
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en-gb
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@nl
P2093
P3181
P356
P1476
Parkin suppresses unfolded pro ...... quitin-protein ligase activity
@en
P2093
P304
P3181
P356
10.1074/JBC.C000447200
P407
P577
2000-11-17T00:00:00Z