A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin - Wikidata - awgldk - TriplyDB

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

http://www.wikidata.org/entity/Q24308676

about

Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative disease The protein interacting with C-kinase (PICK1) interacts with and attenuates parkin-associated endothelial-like (PAEL) receptor-mediated cell death SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates HECT and RING finger families of E3 ubiquitin ligases at a glance Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1 The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology Icariin induces synoviolin expression through NFE2L1 to protect neurons from ER stress-induced apoptosis Parkin reverses intracellular beta-amyloid accumulation and its negative effects on proteasome function.Serine residues in the cytosolic tail of the T-cell antigen receptor alpha-chain mediate ubiquitination and endoplasmic reticulum-associated degradation of the unassembled protein.Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation.Targeting of gp78 for ubiquitin-mediated proteasomal degradation by Hrd1: cross-talk between E3s in the endoplasmic reticulum.The Unfolded Protein Response, Degradation from Endoplasmic Reticulum and Cancer Toxoplasma gondii prevalent in China induce weaker apoptosis of neural stem cells C17.2 via endoplasmic reticulum stress (ERS) signaling pathways.Effects of oxidative stress on the solubility of HRD1, a ubiquitin ligase implicated in Alzheimer's disease Ubiquitin ligases, critical mediators of endoplasmic reticulum-associated degradation Activation of OASIS family, ER stress transducers, is dependent on its stabilization Familial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.E3 ubiquitin ligases in protein quality control mechanism.Signaling pathways from the endoplasmic reticulum and their roles in disease Membrane Protein Quantity Control at the Endoplasmic Reticulum.Aberrant neuronal differentiation and inhibition of dendrite outgrowth resulting from endoplasmic reticulum stress.The Parkinson's disease-associated GPR37 receptor-mediated cytotoxicity is controlled by its intracellular cysteine-rich domain.HRD1 levels increased by zonisamide prevented cell death and caspase-3 activation caused by endoplasmic reticulum stress in SH-SY5Y cells.RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of beta-integrin.Regulation of G Protein-Coupled Receptors by Ubiquitination.Evolutionary divergence of valosin-containing protein/cell division cycle protein 48 binding interactions among endoplasmic reticulum-associated degradation proteins.Ketoconazole induces apoptosis in rat cardiomyocytes through reactive oxygen species-mediated parkin overexpression.Neuroprotection by Endoplasmic Reticulum Stress-Induced HRD1 and Chaperones: Possible Therapeutic Targets for Alzheimer's and Parkinson's Disease.Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD).GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant.Mice lacking Gpr37 exhibit decreased expression of the myelin-associated glycoprotein MAG and increased susceptibility to demyelination.

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P2860

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

http://www.wikidata.org/entity/Q24308676

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@ast

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en-gb

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@nl

type

label

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@ast

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en-gb

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@nl

prefLabel

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@ast

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en-gb

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@nl

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P356

J.1471-4159.2006.04155.X

P1433

Journal of Neurochemistry

P1476

A ubiquitin ligase HRD1 promotes the degradation of Pael receptor, a substrate of Parkin

@en

P2093

Akihisa Hata

http://www.w3.org/2001/XMLSchema#string

Karin Murahashi

http://www.w3.org/2001/XMLSchema#string

Kazuo Nagashima

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Kyoko Kubota

http://www.w3.org/2001/XMLSchema#string

Noboru Fujitani

http://www.w3.org/2001/XMLSchema#string

Ryosuke Takahashi

http://www.w3.org/2001/XMLSchema#string

Satoshi Matsumura

http://www.w3.org/2001/XMLSchema#string

Takashi Uehara

http://www.w3.org/2001/XMLSchema#string

Tomohiro Omura

http://www.w3.org/2001/XMLSchema#string

Yasuko Orba

http://www.w3.org/2001/XMLSchema#string

P2860

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Human HRD1 protects against ER stress-induced apoptosis through ER-associated degradation

P304

1456-1469

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scholarly article

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10.1111/J.1471-4159.2006.04155.X

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P433

6

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99

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Masayuki Kaneko

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2006-10-24T00:00:00Z

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6735630

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17059562

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P921

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

G protein-coupled receptor 37