Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating
about
Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4Ito channels are octomeric complexes with four subunits of each Kv4.2 and K+ channel-interacting protein 2Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)Ca2+-dependent block of CREB-CBP transcription by repressor DREAM.Multiprotein assembly of Kv4.2, KChIP3 and DPP10 produces ternary channel complexes with ISA-like propertiesA role for frequenin, a Ca2+-binding protein, as a regulator of Kv4 K+-currentsThree-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamerA VAMP7/Vti1a SNARE complex distinguishes a non-conventional traffic route to the cell surface used by KChIP1 and Kv4 potassium channelsTraffic of Kv4 K+ channels mediated by KChIP1 is via a novel post-ER vesicular pathwayStructural Insights into KChIP4a Modulation of Kv4.3 InactivationTwo arginines in the cytoplasmic C-terminal domain are essential for voltage-dependent regulation of A-type K+ current in the Kv4 channel subfamilyEffective association of Kv channel-interacting proteins with Kv4 channel is mediated with their unique core peptidePalmitoylation of KChIP splicing variants is required for efficient cell surface expression of Kv4.3 channelsTuning pacemaker frequency of individual dopaminergic neurons by Kv4.3L and KChip3.1 transcriptionC-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2Augmentation of Kv4.2-encoded currents by accessory dipeptidyl peptidase 6 and 10 subunits reflects selective cell surface Kv4.2 protein stabilizationDipeptidyl peptidase-like protein 6 is required for normal electrophysiological properties of cerebellar granule cellsInhibitory effects of polyunsaturated fatty acids on Kv4/KChIP potassium channels.Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant mannerFunctional and pharmacological characterization of a Shal-related K+ channel subunit in ZebrafishMolecular determinants of cardiac transient outward potassium current (I(to)) expression and regulationMulti-walled carbon nanotubes impair Kv4.2/4.3 channel activities, delay membrane repolarization and induce bradyarrhythmias in the rat.Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a.K(V)4.2 channels tagged in the S1-S2 loop for alpha-bungarotoxin binding provide a new tool for studies of channel expression and localization.Roles of KChIP1 in the regulation of GABA-mediated transmission and behavioral anxiety.The tetramerization domain potentiates Kv4 channel function by suppressing closed-state inactivation.Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexesModulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806.DPP10 splice variants are localized in distinct neuronal populations and act to differentially regulate the inactivation properties of Kv4-based ion channelsK(V)4.3 N-terminal deletion mutant Δ2-39: effects on inactivation and recovery characteristics in both the absence and presence of KChIP2b.A-type potassium currents in smooth muscle.The "structurally minimal" isoform KChIP2d modulates recovery of K(v)4.3 N-terminal deletion mutant Δ2-39Impact of KChIP2 on Cardiac Electrophysiology and the Progression of Heart Failure.The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.Determinants of voltage-gated potassium channel surface expression and localization in Mammalian neurons.Transient outward potassium current, 'Ito', phenotypes in the mammalian left ventricle: underlying molecular, cellular and biophysical mechanisms.Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel.KChIP2 genotype dependence of transient outward current (Ito) properties in cardiomyocytes isolated from male and female mice.Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic RoleGating charge immobilization in Kv4.2 channels: the basis of closed-state inactivation.
P2860
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P2860
Conserved Kv4 N-terminal domain critical for effects of Kv channel-interacting protein 2.2 on channel expression and gating
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Conserved Kv4 N-terminal domai ...... channel expression and gating
@ast
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en-gb
Conserved Kv4 N-terminal domai ...... channel expression and gating
@nl
type
label
Conserved Kv4 N-terminal domai ...... channel expression and gating
@ast
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en-gb
Conserved Kv4 N-terminal domai ...... channel expression and gating
@nl
prefLabel
Conserved Kv4 N-terminal domai ...... channel expression and gating
@ast
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en-gb
Conserved Kv4 N-terminal domai ...... channel expression and gating
@nl
P2093
P2860
P356
P1476
Conserved Kv4 N-terminal domai ...... channel expression and gating
@en
P2093
P2860
P304
P356
10.1074/JBC.M101320200
P407
P577
2001-06-29T00:00:00Z