Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
about
Human SHPRH is a ubiquitin ligase for Mms2-Ubc13-dependent polyubiquitylation of proliferating cell nuclear antigenThe HECT domain of TRIP12 ubiquitinates substrates of the ubiquitin fusion degradation pathwayDistinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1AMolecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylationUbc13: the Lys63 ubiquitin chain building machineUEV-1 is an ubiquitin-conjugating enzyme variant that regulates glutamate receptor trafficking in C. elegans neuronsStructural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10Structure and functional interactions of the Tsg101 UEV domain.Structure and Ubiquitin Interactions of the Conserved Zinc Finger Domain of Npl4Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78E2 interaction and dimerization in the crystal structure of TRAF6The structure of the catalytic subunit FANCL of the Fanconi anemia core complexStructural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia PathwayThe mechanism of OTUB1-mediated inhibition of ubiquitinationDoa1 is a Cdc48 adapter that possesses a novel ubiquitin binding domainStructural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO.Cue1p is an activator of Ubc7p E2 activity in vitro and in vivo.Characterization of a UBC13 kinase in Plasmodium falciparumAn NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysisEnhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 proteinA single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complexE2s: structurally economical and functionally repleteProtein-protein interaction antagonists as novel inhibitors of non-canonical polyubiquitylationMms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formationOverview of protein structural and functional folds.Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation.Anatomy of the E2 ligase fold: implications for enzymology and evolution of ubiquitin/Ub-like protein conjugationAutomated clustering of probe molecules from solvent mapping of protein surfaces: new algorithms applied to hot-spot mapping and structure-based drug design.Identification of a protein essential for a major pathway used by human cells to avoid UV- induced DNA damageA ubiquitin E2 variant protein acts in axon termination and synaptogenesis in Caenorhabditis elegansTR-FRET-based high-throughput screening assay for identification of UBC13 inhibitors.Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimerUbiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation.RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor RecruitmentUbiquitin in motion: structural studies of the ubiquitin-conjugating enzyme∼ubiquitin conjugate.Versatile roles of k63-linked ubiquitin chains in trafficking.The HIP2~ubiquitin conjugate forms a non-compact monomeric thioester during di-ubiquitin synthesis.Getting into position: the catalytic mechanisms of protein ubiquitylation.Ubiquitin-like protein activation.
P2860
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P2860
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
description
2001 nî lūn-bûn
@nan
2001 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@ast
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en-gb
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@nl
type
label
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@ast
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en-gb
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@nl
prefLabel
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@ast
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en-gb
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@nl
P2093
P3181
P356
P1476
Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13
@en
P2093
J N Glover
L Pastushok
M J Ellison
R A Edwards
T F Moraes
P2888
P304
P3181
P356
10.1038/90373
P407
P577
2001-08-01T00:00:00Z
P5875
P6179
1000226640