The mechanism of OTUB1-mediated inhibition of ubiquitination
about
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesisOTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinOTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysisUbiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysisOTUB1 modulates c-IAP1 stability to regulate signalling pathwaysMolecular insights into the function of RING finger (RNF)-containing proteins hRNF8 and hRNF168 in Ubc13/Mms2-dependent ubiquitylationUbc13: the Lys63 ubiquitin chain building machineWriters, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break RepairRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINFine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at workDeubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and ActivityDeubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cellsE2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymesMolecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne.Ubiquitylation, neddylation and the DNA damage responseFIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1Ubiquitin chain conformation regulates recognition and activity of interacting proteinsComplex structure of OspI and Ubc13: the molecular basis of Ubc13 deamidation and convergence of bacterial and host E2 recognitionCrystal Structure of a Ube2S-Ubiquitin ConjugatePlasmodium falciparum OTU-like cysteine protease (PfOTU) is essential for apicoplast homeostasis and associates with noncanonical role of Atg8Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.The regulation of TGF-β/SMAD signaling by protein deubiquitination.Proteomic profile of pre - B2 lymphoblasts from children with acute lymphoblastic leukemia (ALL) in relation with the translocation (12; 21)The Fanconi Anemia DNA Repair Pathway Is Regulated by an Interaction between Ubiquitin and the E2-like Fold Domain of FANCLOTUB1 de-ubiquitinating enzyme promotes prostate cancer cell invasion in vitro and tumorigenesis in vivo.The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages.Activated Protein C Ameliorates Renal Ischemia-Reperfusion Injury by Restricting Y-Box Binding Protein-1 UbiquitinationPTEN regulates RPA1 and protects DNA replication forks.Chromatin modifications and the DNA damage response to ionizing radiation.OTUB1 triggers lung cancer development by inhibiting RAS monoubiquitination.The role of allostery in the ubiquitin-proteasome systemOTUB1 promotes tumor invasion and predicts a poor prognosis in gastric adenocarcinoma.OTUB1 enhances TGFβ signalling by inhibiting the ubiquitylation and degradation of active SMAD2/3.Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.Enzymatic production of mono-ubiquitinated proteins for structural studies: The example of the Josephin domain of ataxin-3.Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.OTUB1-catalyzed deubiquitination of FOXM1 facilitates tumor progression and predicts a poor prognosis in ovarian cancer.The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics
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P2860
The mechanism of OTUB1-mediated inhibition of ubiquitination
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
The mechanism of OTUB1-mediated inhibition of ubiquitination
@ast
The mechanism of OTUB1-mediated inhibition of ubiquitination
@en
The mechanism of OTUB1-mediated inhibition of ubiquitination
@nl
type
label
The mechanism of OTUB1-mediated inhibition of ubiquitination
@ast
The mechanism of OTUB1-mediated inhibition of ubiquitination
@en
The mechanism of OTUB1-mediated inhibition of ubiquitination
@nl
prefLabel
The mechanism of OTUB1-mediated inhibition of ubiquitination
@ast
The mechanism of OTUB1-mediated inhibition of ubiquitination
@en
The mechanism of OTUB1-mediated inhibition of ubiquitination
@nl
P2093
P2860
P3181
P356
P1433
P1476
The mechanism of OTUB1-mediated inhibition of ubiquitination
@en
P2093
Reuven Wiener
Xiangbin Zhang
P2860
P2888
P304
P3181
P356
10.1038/NATURE10911
P407
P577
2012-02-22T00:00:00Z
P5875
P6179
1008588394