Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains
about
Involvement of transmembrane domain interactions in signal transduction by alpha/beta integrinsDisruption of the integrin alphaLbeta2 transmembrane domain interface by beta2 Thr-686 mutation activates alphaLbeta2 and promotes micro-clustering of the alphaL subunitsDimerization of the transmembrane domain of Integrin alphaIIb subunit in cell membranesStructure and function of the platelet integrin alphaIIbbeta3Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet.A specific interface between integrin transmembrane helices and affinity for ligandSolution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunitsStructural insight into the interaction between platelet integrin alphaIIbbeta3 and cytoskeletal protein skeleminNMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tailsStructure of an integrin IIb 3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activationNMR analysis of the IIb 3 cytoplasmic interaction suggests a mechanism for integrin regulationTyrosine Phosphorylation as a Conformational Switch: A CASE STUDY OF INTEGRIN 3 CYTOPLASMIC TAILStructures and Interaction Analyses of Integrin M 2 Cytoplasmic TailsPlatelet integrin alpha(IIb)beta(3): activation mechanismsDistinct roles for the alpha and beta subunits in the functions of integrin alphaMbeta2Nanodiscs and Solution NMR: preparation, application and challenges.Construction of covalent membrane protein complexes and high-throughput selection of membrane mimics.Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach.Topographic prominence as a method for cluster identification in single-molecule localisation data.Construction of a series of vectors for high throughput cloning and expression screening of membrane proteins from Mycobacterium tuberculosis.The GPIIb/IIIa (integrin alphaIIbbeta3) odyssey: a technology-driven saga of a receptor with twists, turns, and even a bend.Consensus motif for integrin transmembrane helix associationA push-pull mechanism for regulating integrin function.Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering.Noninvasive measurements of integrin microclustering under altered membrane cholesterol levels.Intermolecular transmembrane domain interactions activate integrin αIIbβ3.The final steps of integrin activation: the end gameSpecificity for homooligomer versus heterooligomer formation in integrin transmembrane helicesNMR structures of the second transmembrane domain of the human glycine receptor alpha(1) subunit: model of pore architecture and channel gating.Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).Tests of integrin transmembrane domain homo-oligomerization during integrin ligand binding and signalingP-selectin glycoprotein ligand-1 forms dimeric interactions with E-selectin but monomeric interactions with L-selectin on cell surfaces.Integrin activation takes shape.CW-EPR studies revealed different motional properties and oligomeric states of the integrin β1a transmembrane domain in detergent micelles or liposomesTransmembrane and Juxtamembrane Structure of αL Integrin in Bicelles.How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles.Integrins, cations and ligands: making the connection.Integrin activation by talin.The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2.Localized lipid packing of transmembrane domains impedes integrin clustering.
P2860
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P2860
Oligomerization of the integrin alphaIIbbeta3: roles of the transmembrane and cytoplasmic domains
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
name
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@ast
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en-gb
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@nl
type
label
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@ast
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en-gb
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@nl
prefLabel
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@ast
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en-gb
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@nl
P2093
P2860
P921
P356
P1476
Oligomerization of the integri ...... mbrane and cytoplasmic domains
@en
P2093
P2860
P304
P356
10.1073/PNAS.221463098
P407
P577
2001-10-23T00:00:00Z