Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet.
about
Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimeraPlatelets and platelet adhesion molecules: novel mechanisms of thrombosis and anti-thrombotic therapiesJuxtamembrane basic residues in glycoprotein Ibbeta cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex.Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complexBernard-Soulier syndromeGenetics of familial forms of thrombocytopenia.Platelets with a W127X mutation in GPIX express sufficient residual amounts of GPIbα to support adhesion to von Willebrand factor and collagen.Inherited thrombocytopenias frequently diagnosed in adults.Molecular basis of inherited thrombocytopenias.Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond.Metalloproteolytic receptor shedding…platelets "acting their age".Zebrafish von Willebrand factor.Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha.Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex.The organizing principle of the platelet glycoprotein Ib-IX-V complex.Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10.Calmodulin adopts an extended conformation when interacting with L-selectin in membranes.L-selectin transmembrane and cytoplasmic domains are monomeric in membranes.Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex.Platelet glycoprotein Ib beta/IX mediates glycoprotein Ib alpha localization to membrane lipid domain critical for von Willebrand factor interaction at high shearForce-induced on-rate switching and modulation by mutations in gain-of-function von Willebrand diseases.Extracellular matrix proteins in hemostasis and thrombosisStructural basis for the specific inhibition of glycoprotein Ibα shedding by an inhibitory antibodyDefective Association of the Platelet Glycoprotein Ib-IX Complex with the Glycosphingolipid-Enriched Membrane Domain Inhibits Murine Thrombus and Atheroma FormationThe membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor.Platelet receptors and signaling in the dynamics of thrombus formation.Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ibα.Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor.FERM domain of moesin desorbs the basic-rich cytoplasmic domain of l-selectin from the anionic membrane surface.Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib-IX complex clustering and signaling.Rolling cell adhesionParsing the repertoire of GPIb-IX-V disorders.Platelet physiology and antiplatelet agents.Spectrum of the mutations in Bernard-Soulier syndrome.Basic mechanisms of platelet receptor shedding.Rare variants in GP1BB are responsible for autosomal dominant macrothrombocytopenia.The dimerization interface of the glycoprotein Ibβ transmembrane domain corresponds to polar residues within a leucine zipper motif.Epac1-deficient mice have bleeding phenotype and thrombocytes with decreased GPIbβ expressionAnalysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex.
P2860
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P2860
Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet.
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Glycoprotein Ibalpha forms dis ...... bunits in the resting platelet
@nl
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@ast
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@en
type
label
Glycoprotein Ibalpha forms dis ...... bunits in the resting platelet
@nl
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@ast
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@en
prefLabel
Glycoprotein Ibalpha forms dis ...... bunits in the resting platelet
@nl
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@ast
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@en
P2093
P2860
P3181
P1433
P1476
Glycoprotein Ibalpha forms dis ...... units in the resting platelet.
@en
P2093
José A López
Sankaranarayanan Srinivasan
Shi-Zhong Luo
Vahid Afshar-Kharghan
P2860
P304
P3181
P356
10.1182/BLOOD-2006-05-024091
P407
P577
2006-09-28T00:00:00Z