APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex - Wikidata - awgldk - TriplyDB

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

http://www.wikidata.org/entity/Q24291991

about

UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit Identification of a physiological E2 module for the human anaphase-promoting complex An architectural map of the anaphase-promoting complex The Arabidopsis anaphase-promoting complex or cyclosome: molecular and genetic characterization of the APC2 subunit K11-linked ubiquitin chains as novel regulators of cell division Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27 Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiae Mnd2 and Swm1 are core subunits of the Saccharomyces cerevisiae anaphase-promoting complex.The Doc1 subunit is a processivity factor for the anaphase-promoting complex.The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins Genome of crocodilepox virus.Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the anaphase-promoting complex/cyclosome.The ubiquitin system, disease, and drug discovery.Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.Securin and B-cyclin/CDK are the only essential targets of the APC.Proteasome-dependent disruption of the E3 ubiquitin ligase anaphase-promoting complex by HCMV protein pUL21a.Cohesion fatigue explains why pharmacological inhibition of the APC/C induces a spindle checkpoint-dependent mitotic arrest Cytoplasmic localized ubiquitin ligase cullin 7 binds to p53 and promotes cell growth by antagonizing p53 function.In vivo characterization of the nonessential budding yeast anaphase-promoting complex/cyclosome components Swm1p, Mnd2p and Apc9p.Control of the centriole and centrosome cycles by ubiquitination enzymes.Two ubiquitin-conjugating enzymes, UbcP1/Ubc4 and UbcP4/Ubc11, have distinct functions for ubiquitination of mitotic cyclin.Kinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters.RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex Mutual regulation between the spindle checkpoint and APC/C.Getting into position: the catalytic mechanisms of protein ubiquitylation.The APC/C Ubiquitin Ligase: From Cell Biology to Tumorigenesis The ubiquitin-proteasome pathway and plant development.The anaphase-promoting complex: a key factor in the regulation of cell cycle.lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2.Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C Cyclin B3 controls anaphase onset independent of spindle assembly checkpoint in meiotic oocytes.Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1.Regulation of APC/C-Cdh1 and its function in neuronal survival Centrosome function in normal and tumor cells.State of the APC/C: organization, function, and structure.Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats

P2860

0d62b10d3f0ba2858a088933bc10bee0ae43df68 700007a8a4a5e73ca8a77f3c73316e20cbf9aa34 733983fc846f51dedcc88c670a1cd55aa3c9ef2d

P248

Q24324253-48051BA1-D20A-4861-A7D0-76D0DB59EB3F Q24328862-FDC62847-AED8-4806-9D5A-762D9524B4AE Q24539034-86FD3263-28F0-4B2A-8D35-4F01400EDC9B Q24685131-59042273-9F6C-4399-A519-DC2F3A9E4D68 Q26851677-52E7F390-7226-4F1E-8FDB-1FC3A04FEB2D Q26998944-9F98E772-0CAA-4B27-8763-E34F2E140D8E Q27640544-B1CB46CB-26A1-423A-AB81-848E52B62DD2 Q27664919-304FA89B-322B-4C41-830F-DCB8F3645091 Q27931731-7A0CB22E-5612-4E7A-90A7-9B8D68DBB8EB Q27933487-EE692366-3FF1-4D43-9F6A-EDACE22E67DE Q27935255-0807BB3E-B4A3-4C62-B304-4331E8EDC19B Q28118953-7A256EC1-AC57-440E-A508-93E7FC2794BA Q28203487-45B323D5-18E2-4E52-B87B-E4726253D739 Q33241222-C1ADB69D-9985-49E7-9DD7-D1C30A0514B6 Q33352698-9D6F395F-4C13-4E2E-8A13-2FC66F95A947 Q33384295-C8D4803C-8EE3-4E36-89A0-E1DA953C54A3 Q34230579-B4205E1C-BE87-45DE-9191-CFCD5AE6E3B6 Q34278659-F6A322FD-2211-446C-983B-280CD4165E76 Q34335500-470AB950-6FC5-404C-AC4D-ECBB421EE746 Q34473920-87B44EFA-F5BA-42A7-A89A-FAE48314ED6D Q34503453-1E6D5044-7454-4BA0-91AB-79E72458E179 Q34576409-E2EDB702-A452-4752-921A-9D12E5BDB18A Q34818293-90A6C18E-3FE8-416F-9355-389295956428 Q35148624-8BDF339D-198F-4E67-8534-45280490D65A Q35158848-128D91A4-FACA-4805-B86A-2DC48017DBC7 Q35567086-BFE6249C-0E46-490A-82DA-B73065E463A7 Q35576429-6CA3C0DB-7D0B-4F02-9D29-F7653A2B1BD7 Q35681247-019C1A06-D5C2-418E-BE93-8D82709A74A2 Q35971862-BCF52010-49D4-4923-8965-0B412B64EF8A Q35973064-5FCFADF2-B291-4C30-A98E-CEE331050A64 Q36022931-186AC58C-B3F2-4055-8E63-B8F9516D8C67 Q36023888-3A4C24C0-F0E5-454E-BCCD-EB27D116527E Q36111232-A8A7B3F4-CFDC-46A1-9F7F-90727C84784F Q36137572-4424F98B-71CB-4D47-A6EF-9BF8642A4AF6 Q36187928-574469B4-19C1-4D1C-86BC-B4B8A724EFB1 Q36378304-9E048391-3AB7-413A-B18C-A8A6E1E8FC00 Q36394421-997DECB2-CB55-47A9-A8C7-AF0A1509E3E4 Q36525898-BC734BC3-55B8-40F5-AEFE-0E23416BC232 Q36867692-7BE77D96-DBBF-42AE-A035-127F0DD0A51B Q37114781-683A9603-09EE-4E4C-BF16-7D07C951C386

P2860

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

http://www.wikidata.org/entity/Q24291991

description

2001 nî lūn-bûn

@nan

2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年学术文章

@wuu

2001年学术文章

@zh-cn

2001年学术文章

@zh-hans

2001年学术文章

@zh-my

2001年学术文章

@zh-sg

2001年學術文章

@yue

name

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@ast

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en-gb

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@nl

type

label

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@ast

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en-gb

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@nl

prefLabel

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@ast

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en-gb

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@nl

P1433

Q24291991-688ED120-AC6C-4BC4-BF0E-81720881B5CF

P1476

Q24291991-CBFA0E7F-8C8A-4E2C-8D37-B04AB76D24D1

P2093

Q24291991-1F1A3A2D-0630-439C-A9F8-7E08D80A89F5

Q24291991-48EFB5D6-DB1D-4536-981C-832BF61B5719

Q24291991-9D8B8798-403F-45E7-AE3A-563F09F3659A

Q24291991-A1361444-5DAB-4500-BDB2-9DA3630FA457

Q24291991-C745B3FA-7194-4AE1-8429-A1E6C949EBCB

Q24291991-DBD5F6D9-97D9-4A9D-A609-ACBB8DA09626

Q24291991-DF855F5D-5274-4C00-B219-D3F429204C49

P2860

Q24291991-00E6D2A4-E452-41D2-9B61-B914CCDD5177

Q24291991-01D55103-87CB-4D5C-8695-81B69A7FE997

Q24291991-020F01FD-66FA-48AD-8501-B36A6861A10D

Q24291991-056FDB19-A418-445A-A72B-94ABD0774E15

Q24291991-0AF4AE95-0205-455A-AE30-A91020872C0E

Q24291991-0CCFC890-AB4C-4BBC-B588-C4ACA09ABDC4

Q24291991-11463DC3-5B36-42F6-9467-E8B30F0C6620

Q24291991-17B4B3EC-38AD-4ADC-969F-BA3365D024A3

Q24291991-1B438EFA-7EAA-438F-852D-3F53F587EC1E

Q24291991-21B0F4E2-ACCA-4685-B876-AA12779EE7AE

P304

Q24291991-FDAE9145-3AC2-45D5-8861-2A2D43A3E5AE

P31

Q24291991-284A03E8-A6AD-434C-8C42-032E35C80F7D

P3181

Q24291991-8B635F80-8E2A-4153-BB47-0DF6555AFA77

P356

Q24291991-EDFF16B0-D64A-45D6-970B-624033D13D95

P407

Q24291991-8915666E-C0D5-4FD1-B021-8C380083F8F6

P433

Q24291991-249BD2C1-A575-4894-A6DA-FDACFAB209B0

P478

Q24291991-747E97F6-9F1C-4583-B4B8-DD9E5034A5E9

P50

Q24291991-1BC3A567-2322-40F3-BC0C-FF86FD3716A0

P577

Q24291991-7BF4932E-0891-4941-8151-FE552AB9599A

P5875

Q24291991-89B0E2EF-903E-4AF8-B641-2DB194326AE7

P698

Q24291991-2FFBF29C-1078-48F8-AC4A-B59D75E6E9C9

P921

Q24291991-13B6762C-EF37-47A7-A91C-81D016382213

Q24291991-DA50337F-8BBA-41AB-B574-6404FEBF0A5B

P932

Q24291991-E98DD553-5AD9-4927-8383-7DBC7A01301F

P3181

P356

P1433

Molecular Biology of the Cell

P1476

APC2 Cullin protein and APC11 ...... the anaphase-promoting complex

@en

P2093

B Li

http://www.w3.org/2001/XMLSchema#string

E Ozkan

http://www.w3.org/2001/XMLSchema#string

H Yu

http://www.w3.org/2001/XMLSchema#string

H Zhu

http://www.w3.org/2001/XMLSchema#string

K Hakala

http://www.w3.org/2001/XMLSchema#string

R Bharadwaj

http://www.w3.org/2001/XMLSchema#string

Z Tang

http://www.w3.org/2001/XMLSchema#string

P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

CDC27Hs colocalizes with CDC16Hs to the centrosome and mitotic spindle and is essential for the metaphase to anaphase transition

Dominant-negative cyclin-selective ubiquitin carrier protein E2-C/UbcH10 blocks cells in metaphase

Cloning, Zn2+ binding, and structural characterization of the guanine nucleotide exchange factor human Mss4

cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family

P304

3839-51

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1615973

http://www.w3.org/2001/XMLSchema#string

P356

10.1091/MBC.12.12.3839

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P50

Johann Deisenhofer

P577

2001-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

11616447

http://www.w3.org/2001/XMLSchema#string

P698

11739784

http://www.w3.org/2001/XMLSchema#string

P921

ubiquitin-protein transferase activity

Anaphase promoting complex subunit 11

P932

60759

http://www.w3.org/2001/XMLSchema#string