Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases. - Wikidata - awgldk - TriplyDB

Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.

Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.

http://www.wikidata.org/entity/Q34230579

about

Turning the RING domain protein MdmX into an active ubiquitin-protein ligase UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor Autoregulation of Parkin activity through its ubiquitin-like domain Members of the E2D (UbcH5) family mediate the ubiquitination of the conserved cysteine of Pex5p, the peroxisomal import receptor A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system UBE2W interacts with FANCL and regulates the monoubiquitination of Fanconi anemia protein FANCD2 Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network HECT and RING finger families of E3 ubiquitin ligases at a glance RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination Protein monoubiquitination and polyubiquitination generate structural diversity to control distinct biological processes Atomic structure of the APC/C and its mechanism of protein ubiquitination.Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78 Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2 Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex RING domain dimerization is essential for RNF4 function Molecular Basis for the Association of Human E4B U Box Ubiquitin Ligase with E2-Conjugating Enzymes UbcH5c and Ubc4 A Dual E3 Mechanism for Rub1 Ligation to Cdc53 BIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimer Structural Determinants of Ubiquitin Conjugation in Entamoeba histolytica A conserved asparagine has a structural role in ubiquitin-conjugating enzymes Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms Structural Insights into the Conformation and Oligomerization of E2∼Ubiquitin Conjugates Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3 E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1 The essential Ubc4/Ubc5 function in yeast is HECT E3-dependent, and RING E3-dependent pathways require only monoubiquitin transfer by Ubc4.Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.A C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125 Structural position correlation analysis (SPCA) for protein family Building ubiquitin chains: E2 enzymes at work The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.An automated approach to network features of protein structure ensembles Paths of long-range communication in the E2 enzymes of family 3: a molecular dynamics investigation.Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS target Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer

P2860

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P2860

Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.

http://www.wikidata.org/entity/Q34230579

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

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Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

@en

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

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type

label

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

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Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

@en

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

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prefLabel

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

@ast

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

@en

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

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P1433

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PNAS.0509418102

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Mechanistic insight into the a ...... y RING-type ubiquitin ligases.

@en

P2093

Engin Ozkan

http://www.w3.org/2001/XMLSchema#string

Hongtao Yu

http://www.w3.org/2001/XMLSchema#string

P2860

ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

APC2 Cullin protein and APC11 RING protein comprise the minimal ubiquitin ligase module of the anaphase-promoting complex

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

An altered-specificity ubiquitin-conjugating enzyme/ubiquitin-protein ligase pair

N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome

Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34

Why bother about clumsiness? The implications of having developmental coordination disorder (DCD)

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

P304

18890-18895

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scholarly article

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10.1073/PNAS.0509418102

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P407

P433

52

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102

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Johann Deisenhofer

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2005-12-19T00:00:00Z

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7405938

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16365295

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P932

1316884

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