The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.
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hNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNAA protein interaction framework for human mRNA degradationSequence-specific RNA binding mediated by the RNase PH domain of components of the exosomeTranslational repression precedes and is required for ZAP-mediated mRNA decayMPP6 is an exosome-associated RNA-binding protein involved in 5.8S rRNA maturationThe association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminusNematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpSThe scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatasesDegradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathwaysAssembly of AUF1 with eIF4G-poly(A) binding protein complex suggests a translation function in AU-rich mRNA decayMetal determines efficiency and substrate specificity of the nuclear NUDIX decapping proteins X29 and H29K (Nudt16)Interaction between Ski7p and Upf1p is required for nonsense-mediated 3'-to-5' mRNA decay in yeastIdentification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3LGrowth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56The zinc-finger antiviral protein recruits the RNA processing exosome to degrade the target mRNANot1 mediates recruitment of the deadenylase Caf1 to mRNAs targeted for degradation by tristetraprolinAU-rich elements and associated factors: are there unifying principles?Domain interactions within the Ski2/3/8 complex and between the Ski complex and Ski7pThe hDcp2 protein is a mammalian mRNA decapping enzymeHighly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilizationContribution of domain structure to the RNA 3' end processing and degradation functions of the nuclear exosome subunit Rrp6p.Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structuresCUG-BP binds to RNA substrates and recruits PARN deadenylaseTethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayThe ARE-dependent mRNA-destabilizing activity of BRF1 is regulated by protein kinase BThe Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cellsMicroRNA targets in immune genes and the Dicer/Argonaute and ARE machinery componentsChaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decayTristetraprolin and its family members can promote the cell-free deadenylation of AU-rich element-containing mRNAs by poly(A) ribonucleaseStress granules and processing bodies are dynamically linked sites of mRNP remodelingA role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayA view to a kill: structure of the RNA exosome.Domain analysis of the chloroplast polynucleotide phosphorylase reveals discrete functions in RNA degradation, polyadenylation, and sequence homology with exosome proteinsDcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathwayOverexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNAThe association of Alu repeats with the generation of potential AU-rich elements (ARE) at 3' untranslated regionsCompeting Interactions of RNA-Binding Proteins, MicroRNAs, and Their Targets Control Neuronal Development and FunctionThe 3' to 5' Exoribonuclease DIS3: From Structure and Mechanisms to Biological Functions and Role in Human Disease
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P2860
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.
description
2002 nî lūn-bûn
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2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2002 թվականի հունվարին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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name
The mammalian exosome mediates ...... that contain AU-rich elements
@nl
The mammalian exosome mediates ...... that contain AU-rich elements.
@ast
The mammalian exosome mediates ...... that contain AU-rich elements.
@en
The mammalian exosome mediates ...... that contain AU-rich elements.
@en-gb
type
label
The mammalian exosome mediates ...... that contain AU-rich elements
@nl
The mammalian exosome mediates ...... that contain AU-rich elements.
@ast
The mammalian exosome mediates ...... that contain AU-rich elements.
@en
The mammalian exosome mediates ...... that contain AU-rich elements.
@en-gb
prefLabel
The mammalian exosome mediates ...... that contain AU-rich elements
@nl
The mammalian exosome mediates ...... that contain AU-rich elements.
@ast
The mammalian exosome mediates ...... that contain AU-rich elements.
@en
The mammalian exosome mediates ...... that contain AU-rich elements.
@en-gb
P2093
P2860
P921
P3181
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P1476
The mammalian exosome mediates ...... that contain AU-rich elements.
@en
P2093
Carol S Lutz
Devi Mukherjee
Ger Pruijn
J Patrick O'Connor
Jeffrey Wilusz
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P304
P3181
P356
10.1093/EMBOJ/21.1.165
P407
P577
2002-01-01T00:00:00Z