Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
about
Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing components and its dominant-negative mutant caused two-cell-stage embryonic arresthNUDT16: a universal decapping enzyme for small nucleolar RNA and cytoplasmic mRNAConservation of the deadenylase activity of proteins of the Caf1 family in humanA protein interaction framework for human mRNA degradationIdentification of a human cytoplasmic poly(A) nuclease complex stimulated by poly(A)-binding protein7-methylguanosine diphosphate (m(7)GDP) is not hydrolyzed but strongly bound by decapping scavenger (DcpS) enzymes and potently inhibits their activityAtaxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granulesNematode m7GpppG and m3(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpSMultiple mRNA decapping enzymes in mammalian cellsCoordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1Metal determines efficiency and substrate specificity of the nuclear NUDIX decapping proteins X29 and H29K (Nudt16)Evolutionary conservation supports ancient origin for Nudt16, a nuclear-localized, RNA-binding, RNA-decapping enzymeThe C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoaMechanistic and kinetic analysis of the DcpS scavenger decapping enzymeHuman Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodiesLIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencingA role for eIF4E and eIF4E-transporter in targeting mRNPs to mammalian processing bodies.A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.Functional characterization of the mammalian mRNA decapping enzyme hDcp2The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodiesFunctional analysis of mRNA scavenger decapping enzymes.Tethering KSRP, a decay-promoting AU-rich element-binding protein, to mRNAs elicits mRNA decayCytoplasmic foci are sites of mRNA decay in human cellsA role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decayThe deacetylase HDAC6 is a novel critical component of stress granules involved in the stress responseMicroRNA-dependent localization of targeted mRNAs to mammalian P-bodiesHuman TOB, an antiproliferative transcription factor, is a poly(A)-binding protein-dependent positive regulator of cytoplasmic mRNA deadenylationDcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathwayRNA granulesIdentification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodiesAn Emerging Role of micro-RNA in the Effect of the Endocrine DisruptorsNew insights into decapping enzymes and selective mRNA decayThe function of RNA-binding proteins at the synapse: implications for neurodegenerationAspergillus oryzae AoSO is a novel component of stress granules upon heat stress in filamentous fungiCrystal structures of the novel cytosolic 5'-nucleotidase IIIB explain its preference for m7GMPThe P body protein Dcp1a is hyper-phosphorylated during mitosismRNA capping: biological functions and applicationsCrystal structure of Dcp1p and its functional implications in mRNA decappingDCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoaThe structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex
P2860
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P2860
Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
description
2002 nî lūn-bûn
@nan
2002 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@ast
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@en
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@nl
type
label
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@ast
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@en
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@nl
prefLabel
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@ast
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@en
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@nl
P2093
P2860
P3181
P356
P1433
P1476
Human Dcp2: a catalytically ac ...... pecific cytoplasmic structures
@en
P2093
Elmar Wahle
Erwin van Dijk
Nicolas Cougot
Sylke Meyer
Sylvie Babajko
P2860
P304
P3181
P356
10.1093/EMBOJ/CDF678
P407
P577
2002-12-16T00:00:00Z