PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B
about
Evolution and functional divergence of NLRP genes in mammalian reproductive systemsA Shope Fibroma virus PYRIN-only protein modulates the host immune responseChronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytesThe PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulationComparative analysis of apoptosis and inflammation genes of mice and humansEvaluation of Nod-like receptor (NLR) effector domain interactionsCryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASCAIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASCDe novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseasesThe PAAD/PYRIN-family protein ASC is a dual regulator of a conserved step in nuclear factor kappaB activation pathwaysCARD games in apoptosis and immunityNew mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromesThe familial Mediterranean fever protein, pyrin, is cleaved by caspase-1 and activates NF-kappaB through its N-terminal fragmentInflammasomes: too big to missFamilial Mediterranean fever, inflammation and nephrotic syndrome: fibrillary glomerulopathy and the M680I missense mutationNOD-Like Receptors in Infection, Immunity, and DiseasesBiochemical and structural aspects of the ATP-binding domain in inflammasome-forming human NLRP proteinsImmunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activationStructural and Functional Analysis of the NLRP4 Pyrin DomainNALPs: a novel protein family involved in inflammationInflammasome-associated nucleotide-binding domain, leucine-rich repeat proteins and inflammatory diseasesThe PYRIN domain in signal transductionNLRs, inflammasomes, and viral infectionCARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathwaysStructural, expression, and evolutionary analysis of mouse CIAS1Description of a new family with cryopyrin-associated periodic syndrome: risk of visual loss in patients bearing the R260W mutation.Expression analysis of the NLRP gene family suggests a role in human preimplantation development.Bacterial RNA:DNA hybrids are activators of the NLRP3 inflammasomeCARD8 is a negative regulator for NLRP3 inflammasome, but mutant NLRP3 in cryopyrin-associated periodic syndromes escapes the restriction.Increased frequency of Mediterranean fever gene variants in multiple myeloma.Functional screening of five PYPAF family members identifies PYPAF5 as a novel regulator of NF-kappaB and caspase-1.Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.Neonatal-onset multisystem inflammatory disease responsive to interleukin-1beta inhibition.PYNOD, a novel Apaf-1/CED4-like protein is an inhibitor of ASC and caspase-1.The domains of apoptosis: a genomics perspective.PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages.Prevention of cold-associated acute inflammation in familial cold autoinflammatory syndrome by interleukin-1 receptor antagonist.PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion.Pathogenesis of familial periodic fever syndromes or hereditary autoinflammatory syndromes.Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy.
P2860
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P2860
PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年学术文章
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2002年學術文章
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name
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@ast
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en-gb
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@nl
type
label
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@ast
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en-gb
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@nl
prefLabel
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@ast
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en-gb
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@nl
P2093
P2860
P3181
P356
P1476
PYPAF1, a PYRIN-containing Apa ...... lates activation of NF-kappa B
@en
P2093
Amal Al-Garawi
Brad J Geddes
Gulam A Manji
John Bertin
Jose M Lora
Mark Jurman
Melissa Brown
Michael Briskin
P2860
P304
P3181
P356
10.1074/JBC.M112208200
P407
P577
2002-03-29T00:00:00Z