Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription
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Txk, a member of the non-receptor tyrosine kinase of the Tec family, forms a complex with poly(ADP-ribose) polymerase 1 and elongation factor 1alpha and regulates interferon-gamma gene transcription in Th1 cellsSkewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's diseaseDifferentiation of effector CD4 T cell populations (*)Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.Effector CD8+ T cells recovered from an influenza pneumonia differentiate to a state of focused gene expression.The role of Tec family kinases in T cell development and function.TEC-family kinases: regulators of T-helper-cell differentiation.Survival strategy of obligately intracellular Ehrlichia chaffeensis: novel modulation of immune response and host cell cycles.Kinetic analysis of genomewide gene expression reveals molecule circuitries that control T cell activation and Th1/2 differentiation.GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.An insight into molecular mechanisms of human T helper cell differentiation.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkSignals for the execution of Th2 effector function.How diverse--CD4 effector T cells and their functions.The role of Tec family kinases in the regulation of T-helper-cell differentiation.Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics.Genetic expression profiling of six odontogenic tumors.Th1-dominant shift of T cell cytokine production, and subsequent reduction of serum immunoglobulin E response by administration in vivo of plasmid expressing Txk/Rlk, a member of Tec family tyrosine kinases, in a mouse model.Excessive expression of Txk, a member of the Tec family of tyrosine kinases, contributes to excessive Th1 cytokine production by T lymphocytes in patients with Behcet's disease.Involvement of Th1 cells and heat shock protein 60 in the pathogenesis of intestinal Behcet's disease.Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations.Differential expression of mRNA for Th1 and Th2 cytokine-associated transcription factors and suppressors of cytokine signalling in peripheral blood mononuclear cells of patients with atopic dermatitis.Role of Non Receptor Tyrosine Kinases in Hematological Malignances and its Targeting by Natural Products.
P2860
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P2860
Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@ast
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en-gb
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@nl
type
label
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@ast
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en-gb
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@nl
prefLabel
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@ast
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en-gb
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@nl
P2093
P3181
P1476
Txk, a member of nonreceptor t ...... s IFN-gamma gene transcription
@en
P2093
Hiroko Nagafuchi
Jun-ichi Kashiwakura
Mitsuhiro Takeno
Noboru Suzuki
Yuko Takeba
P304
P3181
P356
10.4049/JIMMUNOL.168.5.2365
P407
P577
2002-03-01T00:00:00Z