GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.
about
Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments.Natural genetic variation profoundly regulates gene expression in immune cells and dictates susceptibility to CNS autoimmunity.The non-canonical NF-κB pathway in immunity and inflammation.Small molecules to the rescue: Inhibition of cytokine signaling in immune-mediated diseases.Constitutive expression of NF-κB inducing kinase in regulatory T cells impairs suppressive function and promotes instability and pro-inflammatory cytokine production.Understanding Progressive Multifocal Leukoencephalopathy Risk in Multiple Sclerosis Patients Treated with Immunomodulatory Therapies: A Bird's Eye View.
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GWAS analysis implicates NF-κB-mediated induction of inflammatory T cells in multiple sclerosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 09 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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type
label
GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
@nl
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GWAS analysis implicates NF-κB ...... T cells in multiple sclerosis.
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A H Beecham
E R Martin
J L McCauley
J P Hussman
M A Pericak-Vance
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P2888
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10.1038/GENE.2016.23
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2016-06-09T00:00:00Z