Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
about
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10Pathways towards and away from Alzheimer's diseaseThe Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretaseAmyloidosis in Retinal Neurodegenerative DiseasesA Disintegrin and Metalloprotease (ADAM): Historical Overview of Their FunctionsThe Neuroprotective Properties of the Amyloid Precursor Protein Following Traumatic Brain InjuryAlzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasisA Disintegrin and Metalloprotease 17 in the Cardiovascular and Central Nervous SystemsCurrent and future implications of basic and translational research on amyloid-β peptide production and removal pathwaysThe Ubiquitin-Proteasome System and Molecular Chaperone Deregulation in Alzheimer's DiseasePhenylbutyric acid rescues endoplasmic reticulum stress-induced suppression of APP proteolysis and prevents apoptosis in neuronal cellsGene expression profiling in cells with enhanced gamma-secretase activity.gamma-Secretase dependent production of intracellular domains is reduced in adult compared to embryonic rat brain membranesSAR Studies of Exosite-Binding Substrate-Selective Inhibitors of A Disintegrin And Metalloprotease 17 (ADAM17) and Application as Selective in Vitro Probes.The selective beta1-adrenoceptor antagonist nebivolol is a potential oestrogen receptor agonist with neuroprotective abilitiesThe secretases: enzymes with therapeutic potential in Alzheimer disease.An overview of APP processing enzymes and products.The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortexBeyond the signaling effect role of amyloid-ß42 on the processing of APP, and its clinical implicationsA disintegrin and metalloproteinase 9 is involved in ectodomain shedding of receptor-binding cancer antigen expressed on SiSo cells.Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process.Lowering of amyloid beta peptide production with a small molecule inhibitor of amyloid-β precursor protein dimerizationComparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme ActivityDiscovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates.Inhibition of ADAM10 promotes the clearance of Aβ across the BBB by reducing LRP1 ectodomain shedding.γ-Secretase processing and effects of γ-secretase inhibitors and modulators on long Aβ peptides in cells.Cleavage of neuregulin-1 by BACE1 or ADAM10 protein produces differential effects on myelination.Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.ADAM33: a novel therapeutic target for asthma.Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin.Structural and mechanistic commonalities of amyloid-β and the prion proteinAn integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer's diseaseAll in the Family: How the APPs Regulate NeurogenesisMT5-MMP, ADAM-10, and N-cadherin act in concert to facilitate synapse reorganization after traumatic brain injuryDecreasing the expression of PICALM reduces endocytosis and the activity of β-secretase: implications for Alzheimer's diseaseBryostatin-1 vs. TPPB: dose-dependent APP processing and PKC-α, -δ, and -ε isoform activation in SH-SY5Y neuronal cells.Inhibiting BACE1 to reverse synaptic dysfunctions in Alzheimer's disease.Soluble amyloid precursor protein-α rescues age-linked decline in neural progenitor cell proliferationSubstrate specificity of gamma-secretase and other intramembrane proteases.
P2860
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P2860
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
description
2003 nî lūn-bûn
@nan
2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@ast
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en-gb
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@nl
type
label
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@ast
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en-gb
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@nl
prefLabel
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@ast
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en-gb
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@nl
P2093
P921
P3181
P1476
Putative function of ADAM9, ADAM10, and ADAM17 as APP alpha-secretase
@en
P2093
Chinatsu Hattori
Kei Maruyama
Masashi Asai
Noboru Sasagawa
Sei-ichi Tanuma
Shoichi Ishiura
P3181
P356
10.1016/S0006-291X(02)02999-6
P407
P50
P577
2003-01-31T00:00:00Z